Recombinant Human LRRTM4 protein (His tag) is a Human Fragment protein, in the 1 to 424 aa range, expressed in HEK 293 cells, with >97%, < 1 EU/µg endotoxin level, suitable for SDS-PAGE.
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UNQ3075/PRO9907, LRRTM4, Leucine-rich repeat transmembrane neuronal protein 4
- SDS-PAGE
Supplier Data
SDS-PAGE - Recombinant Human LRRTM4 protein (His tag) (AB276388)
SDS-PAGE analysis of ab276388
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서열 정보
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추가 정보
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
The protein facilitates synapse development and maintenance influencing synaptic transmission by interacting with presynaptic partners. LRRTM4 acts as a synaptic organizer and is part of the postsynaptic membrane complex. It works closely with other synaptic proteins to facilitate synaptogenesis and maintain synaptic plasticity essential for learning and memory processes.
Pathways
LRRTM4 operates within neural communication pathways critical for synaptic development. It interacts with neurexins which are essential to the presynaptic organization forming complexes that aid neurotransmitter release. Furthermore it is involved in the organization of excitatory synapse pathways similar to its relative protein LRRTM2 which also shares a role in excitatory synaptic function.
일반 정보
기능
May play a role in the development and maintenance of the vertebrate nervous system. Exhibits strong synaptogenic activity, restricted to excitatory presynaptic differentiation (By similarity).
서열 유사성
Belongs to the LRRTM family.
타겟 정보
Product promise
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