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AB243774

Recombinant human LTA protein (Active)

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(1 출판물)

Recombinant human LTA protein (Active) is a Human Full Length protein, in the 35 to 205 aa range, expressed in Escherichia coli, with >96%, < 1 EU/µg endotoxin level, suitable for SDS-PAGE, FuncS, HPLC.

대체 명칭 보기

TNFB, TNFSF1, LTA, Lymphotoxin-alpha, LT-alpha, TNF-beta, Tumor necrosis factor ligand superfamily member 1

1 이미지
SDS-PAGE - Recombinant human LTA protein (Active) (AB243774)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant human LTA protein (Active) (AB243774)

SDS Page analysis of LTA with ab243774.

주요 정보

Purity

>96% SDS-PAGE

> 96 % HPLC.

Endotoxin 레벨

< 1 EU/µg

발현 시스템

Escherichia coli

Tags

Tag free

Applications

FuncS, HPLC, SDS-PAGE

applications

Biologically active

Yes

Biological activity

Fully biologically active when compared to standard. The ED50 as determined by a cytotoxicity assay using murine L929 cells is less than 5 pg/ml, corresponding to a specific activity of >2.0x108 IU/mg in the presence of actinomycin D.

Accession

Animal free

No

Carrier free

No

Species

Human

Reconstitution

Reconstitute in water or 0.1% BSA aqueous buffer

보관 버퍼

Constituents: PBS, 0.02% Sorbitan monolaurate, ethoxylated

storage-buffer

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보완 제품

Reagents, Controls & Accessories

AB210899

ELISA Coating Buffer 1X

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Proteins & Peptides

AB316459

Recombinant Human FGL1 Protein Standard

Sandwich ELISA - Recombinant Human FGL1 Protein Standard (AB316459)

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Proteins & Peptides

AB283931

Recombinant Human TNFL9 Protein (Active)

Bioactive

Functional Studies - Recombinant Human TNFL9 Protein (Active) (AB283931)

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  • 0
Proteins & Peptides

AB159764

Recombinant Human OX40L/TNFSF4 protein (GST tag N-Terminus)

SDS-PAGE - Recombinant Human OX40L/TNFSF4 protein (GST tag N-Terminus) (AB159764)

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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "FuncS": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "HPLC": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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제품 세부 정보

This product was previously labelled as TNF beta
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서열 정보

[{"linker":null,"sequence":"LPGVGLTPSAAQTARQHPKMHLAHSTLKPAAHLIGDPSKQNSLLWRANTDRAFLQDGFSLSNNSLLVPTSGIYFVYSQVVFSGKAYSPKATSSPLYLAHEVQLFSSQYPFHVPLLSSQKMVYPGLQEPWLHSMYHGAAFQLTQGDQLSTHTDGIPHLVLSPSTVFFGAFAL","proteinLength":"Full Length","predictedMolecularWeight":"18.7 kDa","actualMolecularWeight":null,"aminoAcidEnd":205,"aminoAcidStart":35,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"P01374","tags":[]}]
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특성 및 보관 정보

제형
Lyophilized
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
-20°C
적절한 장기 보관 조건
-20°C
보관 정보
Avoid freeze / thaw cycle
True
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일반 정보

기능

Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM (PubMed : 9462508). In its heterotrimeric form with LTB binds to TNFRSF3/LTBR (PubMed : 24248355). Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo.

서열 유사성

Belongs to the tumor necrosis factor family.

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제품 프로토콜

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타겟 정보

Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM (PubMed : 9462508). In its heterotrimeric form with LTB binds to TNFRSF3/LTBR (PubMed : 24248355). Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo.
See full target information LTA
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제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Brain : a journal of neurology 145:4287-4307 PubMed35776111

2022

Lymphotoxin-alpha expression in the meninges causes lymphoid tissue formation and neurodegeneration.

Applications

Unspecified application

Species

Unspecified reactive species

Rachel E James Bates,Eleanor Browne,Renee Schalks,Heather Jacobs,Li Tan,Puja Parekh,Roberta Magliozzi,Massimiliano Calabrese,Nicholas D Mazarakis,Richard Reynolds
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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