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AB176031

Recombinant Human MAGEB10 protein (His tag N-Terminus)

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Recombinant Human MAGEB10 protein (His tag N-Terminus) is a Human Full Length protein, in the 1 to 347 aa range, expressed in Escherichia coli, with >85%, suitable for SDS-PAGE, Mass Spec.

대체 명칭 보기

Melanoma-associated antigen B10, MAGE-B10 antigen, MAGEB10

1 이미지
SDS-PAGE - Recombinant Human MAGEB10 protein (His tag N-Terminus) (AB176031)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human MAGEB10 protein (His tag N-Terminus) (AB176031)

15% SDS-PAGE analysis of ab176031 (3μg).

주요 정보

Purity

>85% SDS-PAGE

ab176031 is purified using conventional chromatography techniques

발현 시스템

Escherichia coli

Tags

His tag N-Terminus

Applications

SDS-PAGE, Mass Spec

applications

Biologically active

No

Accession

Animal free

No

Carrier free

No

Species

Human

보관 버퍼

pH: 8 Constituents: 10% Glycerol (glycerin, glycerine), 0.88% Sodium chloride, 0.32% Tris-HCl buffer, 0.02% (R*,R*)-1,4-Dimercaptobutan-2,3-diol, 0.002% PMSF

storage-buffer

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보완 제품

Primary Antibodies

AB133357

Anti-CD11b antibody [EPR1344]

BOND RX™ Validated|RabMAb|Advanced Validation|Recombinant|Lab Essentials|20ul selling size

Multiplex immunohistochemistry - Anti-CD11b antibody [EPR1344] (AB133357)

  • 4
  • 37
Primary Antibodies

AB955

Anti-CD68 antibody [KP1]

Recombinant|Lab Essentials

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD68 antibody [KP1] (AB955)

  • 4
  • 48
Primary Antibodies

AB75813

Anti-NCAM1 antibody [EP2567Y]

BOND RX™ Validated|20ul selling size|RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-NCAM1 antibody [EP2567Y] (AB75813)

  • 4
  • 7
Primary Antibodies

AB134114

Anti-CD19 antibody [EPR5906]

BOND RX™ Validated|RabMAb|Recombinant|Lab Essentials|20ul selling size

Flow Cytometry (Intracellular) - Anti-CD19 antibody [EPR5906] (AB134114)

  • 4
  • 5
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "Mass Spec": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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서열 정보

[{"linker":null,"sequence":"MGSSHHHHHHSSGLVPRGSHMGSMPRGQKSKLRAREKRRQARGGLEDLIDALDILEEEEESPPSASACLKDVFQSSLDGASNNPHGLREAQSTSTSATAASHTRHPEGVNDQMEERPICTQDLEATDSFPRGPVDEKVIILVHYLLYKYQMKEPITKADMLRNVTQMSKSQFPVILSRASEHLELIFGLDLKEVEPNKHIYVLVNKLDLGCDAKLSDETGVPKTGLLMTVLGIIFTNGNCVAEEEVWKVFNTMGLYDGIEHFMFGEPRKLLTKDLVKENYLEYQQVPNSDPPRYQFLWGPRAHAETSKMKVLEFLAKVNDTAPSEFSNWYTEALQDEEERARARVAAKARVSATAGARSKVKSSKSSQLQ","proteinLength":"Full Length","predictedMolecularWeight":"41.4 kDa","actualMolecularWeight":null,"aminoAcidEnd":347,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"Q96LZ2","tags":[{"tag":"His","terminus":"N-Terminus"}]}]
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특성 및 보관 정보

제형
Liquid
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
False
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

MAGEB10 also known as Melanoma Antigen Family B10 belongs to the MAGE family of proteins. This protein has a mass of approximately 40 kDa. MAGEB10 is typically expressed in testis and certain cancerous tissues. It mechanistically interacts with microtubules suggesting a role in cellular structure and motility.
Biological function summary

This protein assists in cellular processes related to proliferation and differentiation. MAGEB10 functions as part of a complex that influences gene transcription regulation. While not fully understood its presence in several tissues indicates it might play roles beyond reproductive biology potentially in tumorigenic processes.

Pathways

Several mechanisms involve MAGEB10 notably the p53 signaling pathway. This protein interacts with p53 an important tumor suppressor affecting apoptosis regulation and cell cycle control. MAGEB10 shares pathway interactions with proteins like MDM2 which further regulates p53 activities emphasizing its role in tumor biology.

Researchers have linked MAGEB10 to certain cancers like melanoma and bladder cancer. Studies show that this protein can interact with tumor-associated antigens such as NY-ESO-1 enhancing its potential as a target for cancer immunotherapy. Understanding these associations helps in developing novel diagnostic and therapeutic approaches.
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일반 정보

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제품 프로토콜

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타겟 정보

See full target information MAGEB10
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Product promise

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