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AB176084

Recombinant Human MPPED2 protein (His tag N-Terminus)

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Recombinant Human MPPED2 protein (His tag N-Terminus) is a Human Full Length protein, in the 1 to 294 aa range, expressed in Escherichia coli, with >85%, suitable for SDS-PAGE, Mass Spec.

대체 명칭 보기

C11orf8, FAM1B, MPPED2, Metallophosphoesterase MPPED2, Fetal brain protein 239, Metallophosphoesterase domain-containing protein 2, 239FB

1 이미지
SDS-PAGE - Recombinant Human MPPED2 protein (His tag N-Terminus) (AB176084)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human MPPED2 protein (His tag N-Terminus) (AB176084)

15% SDS-PAGE analysis of ab176084 (3μg).

주요 정보

Purity

>85% SDS-PAGE

ab176084 is purified using conventional chromatography techniques.

발현 시스템

Escherichia coli

Tags

His tag N-Terminus

Applications

Mass Spec, SDS-PAGE

applications

Biologically active

No

Accession

Animal free

No

Carrier free

No

Species

Human

보관 버퍼

pH: 8 Constituents: 10% Glycerol (glycerin, glycerine), 0.88% Sodium chloride, 0.32% Tris-HCl buffer, 0.02% (R*,R*)-1,4-Dimercaptobutan-2,3-diol

storage-buffer

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보완 제품

Primary Antibodies

AB129153

Anti-HMGA1 antibody [EPR7839]

20ul selling size|Recombinant|Advanced Validation|RabMAb

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-HMGA1 antibody [EPR7839] (AB129153)

  • 5
  • 3
Cell Lines & Lysates

AB266419

Human NDUFS3 knockout HEK-293T cell line

Advanced Validation

Western blot - Human NDUFS3 knockout HEK-293T cell line (AB266419)

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  • 0
Proteins & Peptides

AB158615

Recombinant Human Glycogen synthase 1/GYS1 protein (GST tag N-Terminus)

SDS-PAGE - Recombinant Human Glycogen synthase 1/GYS1 protein (GST tag N-Terminus) (AB158615)

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  • 0
Proteins & Peptides

AB98079

Recombinant Human WDR5 protein (His tag N-Terminus)

SDS-PAGE - Recombinant Human WDR5 protein (His tag N-Terminus) (AB98079)

  • 0
  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "Mass Spec": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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서열 정보

[{"linker":null,"sequence":"MGSSHHHHHHSSGLVPRGSHMGSMAHGIPSQGKVTITVDEYSSNPTQAFTHYNINQSRFQPPHVHMVDPIPYDTPKPAGHTRFVCISDTHSRTDGIQMPYGDILLHTGDFTELGLPSEVKKFNDWLGNLPYEYKIVIAGNHELTFDKEFMADLVKQDYYRFPSVSKLKPEDFDNVQSLLTNSIYLQDSEVTVKGFRIYGAPWTPWFNGWGFNLPRGQSLLDKWNLIPEGIDILMTHGPPLGFRDWVPKELQRVGCVELLNTVQRRVRPKLHVFGGIHEGYGIMTDGYTTYINASTCTVSFQPTNPPIIFDLPNPQGS","proteinLength":"Full Length","predictedMolecularWeight":"35.7 kDa","actualMolecularWeight":null,"aminoAcidEnd":294,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"Q15777","tags":[{"tag":"His","terminus":"N-Terminus"}]}]
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특성 및 보관 정보

제형
Liquid
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
False
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

The metallophosphoesterase domain-containing protein 2 (MPPED2) also known as c10orf59 has a molecular mass of approximately 32 kDa. This protein is characterized by a conserved metallophosphoesterase domain which suggests its role in catalyzing the hydrolysis of phosphomonoester bonds. MPPED2 is expressed in the brain and testis indicating potential roles in neurological and reproductive processes.
Biological function summary

Metallophosphoesterase domain proteins like MPPED2 participate in cellular signal transduction by modulating phosphate group removal. Though it is not widely recognized as part of a larger complex MPPED2's enzymatic activity may influence intracellular signaling pathways that are significant in the nervous system. Its expression patterns suggest it could have specialized roles in neurons or glial cells possibly affecting brain development or function.

Pathways

MPPED2 interacts with signaling networks related to phosphoinositide metabolism and possibly PI3K/AKT pathway. These pathways are central to cell survival growth and metabolism. MPPED2's activity could influence these processes through regulation of phosphate-related signaling intermediates. It may also interact indirectly with proteins like PTEN known for its role in tumor suppression through lipid phosphatase activity.

MPPED2 has been linked to neurodevelopmental abnormalities and cancer. Its expression is altered in some tumor cells hinting at a potential role in oncogenesis. Additionally the protein may interact with other regulatory proteins such as PTEN in a context of disease progression particularly when normal phosphatase activities are disrupted. Understanding MPPED2's exact function could lead to insights into its role in such conditions and possible therapeutic interventions.
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일반 정보

기능

Displays low metallophosphoesterase activity (in vitro). May play a role in the development of the nervous system.

서열 유사성

Belongs to the UPF0046 family.

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제품 프로토콜

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타겟 정보

Displays low metallophosphoesterase activity (in vitro). May play a role in the development of the nervous system.
See full target information MPPED2
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Product promise

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