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AB113164

Recombinant Human NAPG protein (His tag N-Terminus)

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Recombinant Human NAPG protein (His tag N-Terminus) is a Human Full Length protein, in the 1 to 312 aa range, expressed in Escherichia coli, with >95%, suitable for SDS-PAGE, Mass Spec.

대체 명칭 보기

SNAPG, NAPG, Gamma-soluble NSF attachment protein, SNAP-gamma, N-ethylmaleimide-sensitive factor attachment protein gamma

1 이미지
SDS-PAGE - Recombinant Human NAPG protein (His tag N-Terminus) (AB113164)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human NAPG protein (His tag N-Terminus) (AB113164)

ab113164 at 3 µg analysed by 15% SDS PAGE.

주요 정보

Purity

>95% SDS-PAGE

ab113164 was purified by using conventional chromatography

발현 시스템

Escherichia coli

Tags

His tag N-Terminus

Applications

SDS-PAGE, Mass Spec

applications

Biologically active

No

Accession

Animal free

No

Carrier free

No

Species

Human

보관 버퍼

pH: 8 Constituents: 10% Glycerol (glycerin, glycerine), 0.58% Sodium chloride, 0.32% Tris HCl, 0.02% (R*,R*)-1,4-Dimercaptobutan-2,3-diol

storage-buffer

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보완 제품

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Recombinant Human ADRM1/ARM-1 protein (His tag N-Terminus)

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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "Mass Spec": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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서열 정보

[{"linker":null,"sequence":"MGSSHHHHHHSSGLVPRGSHMGSHMAAQKINEGLEHLAKAEKYLKTGFLKWKPDYDSAASEYGKAAVAFKNAKQFEQAKDACLREAVAHENNRALFHAAKAYEQAGMMLKEMQKLPEAVQLIEKASMMYLENGTPDTAAMALERAGKLIENVDPEKAVQLYQQTANVFENEERLRQAVELLGKASRLLVRGRRFDEAALSIQKEKNIYKEIENYPTCYKKTIAQVLVHLHRNDYVAAERCVRESYSIPGFNGSEDCAALEQLLEGYDQQDQDQVSDVCNSPLFKYMDNDYAKLGLSLVVPGGGIKKKSPATPQAKPDGVTATAADEEEDEYSGGLC","proteinLength":"Full Length","predictedMolecularWeight":"37.3 kDa","actualMolecularWeight":null,"aminoAcidEnd":312,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"Q99747","tags":[{"tag":"His","terminus":"N-Terminus"}]}]
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특성 및 보관 정보

제형
Liquid
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
False
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

NAPG also known as N-ethylmaleimide-sensitive factor attachment protein gamma plays an important role in intracellular membrane fusion processes. It facilitates vesicular trafficking by interacting with the SNARE complex. NAPG has a molecular mass of approximately 33 kDa. This protein expresses widely in various tissues with higher levels noted in brain tissue suggesting an important role in neural processes.
Biological function summary

The function of NAPG relates to the mediation of vesicle transport within cells. It forms a part of the SNARE complex which is important for the fusion of transport vesicles with their target membranes. Through its action NAPG ensures the correct delivery of proteins and other molecules to their intended cellular compartments which is essential for maintaining cellular homeostasis and proper signal transduction.

Pathways

NAPG integrates into the SNARE-mediated membrane fusion pathway. This pathway is vital for synaptic vesicle exocytosis and intracellular trafficking across many cell types. NAPG works closely with other SNARE proteins like SNAP-25 and VAMP to ensure the efficiency and precision of vesicular transport and neurotransmitter release.

NAPG has associations with neurodegenerative diseases and disorders involving synaptic dysfunctions. Disruption of NAPG function or expression can lead to impaired neurotransmitter release contributing to conditions such as Alzheimer's disease. Additionally its interaction with proteins like alpha-synuclein highlights its involvement in diseases such as Parkinson's disease where vesicle trafficking is disrupted affecting neuronal communication.
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일반 정보

기능

Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

서열 유사성

Belongs to the SNAP family.

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제품 프로토콜

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타겟 정보

Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.
See full target information NAPG
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Product promise

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