Recombinant Human NHLH2 protein (His tag N-Terminus)
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Recombinant Human NHLH2 protein (His tag N-Terminus) is a Human Full Length protein, in the 1 to 135 aa range, expressed in Escherichia coli, with >90%, suitable for SDS-PAGE, Mass Spec.
대체 명칭 보기
BHLHA34, HEN2, KIAA0490, NHLH2, Helix-loop-helix protein 2, HEN-2, Class A basic helix-loop-helix protein 34, Nescient helix loop helix 2, bHLHa34, NSCL-2
- SDS-PAGE
Unknown
SDS-PAGE - Recombinant Human NHLH2 protein (His tag N-Terminus) (AB156745)
15% SDS-PAGE analysis of 3µg ab156745.
Reactivity 정보
서열 정보
특성 및 보관 정보
제형
배송 시 보관 조건
적절한 단기 보관 기간
적절한 단기 보관 조건
적절한 장기 보관 조건
분주 정보
보관 정보
일반 정보
기능
Transcription factor which binds the E box motif 5'-CA[TC][AG]TG-3'. Involved in regulating energy expenditure, body mass, voluntary physical activity, mating behavior and reproductive longevity, acting through the hypothalamic-pituitary-gonadal axis. Acts as a transcriptional activator of target genes, including NDN, PCSK1, MC4R (By similarity). Is also a transcriptional activator of KISS1 (PubMed : 35066646). May act centrally to regulate function of both white and brown adipose tissue. Together with NHLH1, required to maintain migration and survival of cells in the anterior extramural migration stream (aes), which forms the precerebellar nuclei. Also, in concert with NHLH1, may determine fate of gonadotropin releasing hormone-1 (GnRH-1) neurons.
Subcellular localisation
Nucleus
타겟 정보
Product promise
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