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AB241514

Recombinant Human NT5C1A protein (His tag)

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Recombinant Human NT5C1A protein (His tag) is a Human Full Length protein, in the 1 to 368 aa range, expressed in Yeast, with >90%, suitable for SDS-PAGE.

대체 명칭 보기

Cytosolic 5'-nucleotidase 1A, cN1A, 5'-deoxynucleotidase, Cytosolic 5'-nucleotidase IA, cN-I, cN-IA, NT5C1A

1 이미지
SDS-PAGE - Recombinant Human NT5C1A protein (His tag) (AB241514)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human NT5C1A protein (His tag) (AB241514)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) analysis with 5% enrichment gel and 15% separation gel ab241514.

주요 정보

Purity

>90% SDS-PAGE

발현 시스템

Yeast

Tags

6x His tag N-Terminus

Applications

SDS-PAGE

applications

Biologically active

No

Accession

Animal free

No

Carrier free

No

Species

Human

보관 버퍼

pH: 7.2 - 7.4 Constituents: Tris buffer, 50% Glycerol (glycerin, glycerine)

storage-buffer

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보완 제품

Reagents, Controls & Accessories

AB325997

Prestained Protein Ladder - Extra broad molecular weight (3-250 kDa, 5-color)

SDS-PAGE - Prestained Protein Ladder - Extra broad molecular weight (3-250 kDa, 5-color) (AB325997)

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  • 0
Proteins & Peptides

AB84797

Recombinant human PDGFR alpha protein (GST tag N-Terminus)

Functional Studies - Recombinant human PDGFR alpha protein (AB84797)

  • 0
  • 0
Assay Kits

AB222511

Mouse C Reactive Protein ELISA Kit

Recombinant|SimpleStep

ELISA - Mouse C Reactive Protein ELISA Kit (AB222511)

  • 0
  • 0
Primary Antibodies

AB183734

Anti-GFP antibody [EPR14104]

RabMAb|Recombinant|Lab Essentials|20ul selling size

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GFP antibody [EPR14104] (AB183734)

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Primary Antibodies

AB190214

Anti-NT5C1A antibody

Immunocytochemistry/ Immunofluorescence - Anti-NT5C1A antibody (AB190214)

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  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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서열 정보

[{"linker":null,"sequence":"MEPGQPREPQEPREPGPGAETAAAPVWEEAKIFYDNLAPKKKPKSPKPQNAVTIAVSSRALFRMDEEQQIYTEQGVEEYVRYQLEHENEPFSPGPAFPFVKALEAVNRRLRELYPDSEDVFDIVLMTNNHAQVGVRLINSINHYDLFIERFCMTGGNSPICYLKAYHTNLYLSADAEKVREAIDEGIAAATIFSPSRDVVVSQSQLRVAFDGDAVLFSDESERIVKAHGLDRFFEHEKAHENKPLAQGPLKGFLEALGRLQKKFYSKGLRLECPIRTYLVTARSAASSGARALKTLRSWGLETDEALFLAGAPKGPLLEKIRPHIFFDDQMFHVAGAQEMGTVAAHVPYGVAQTPRRTAPAKQAPSAQ","proteinLength":"Full Length","predictedMolecularWeight":"43 kDa","actualMolecularWeight":null,"aminoAcidEnd":368,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Yeast","accessionNumber":"Q9BXI3","tags":[{"tag":"6x His","terminus":"N-Terminus"}]}]
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특성 및 보관 정보

제형
Liquid
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
-20°C
적절한 장기 보관 조건
-20°C
보관 정보
Avoid freeze / thaw cycle
False
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

NT5C1A also known as cytosolic 5'-nucleotidase 1A is an enzyme involved in the catabolism of nucleotides. It dephosphorylates nucleoside monophosphates into nucleosides and inorganic phosphate. The molecular mass of NT5C1A is approximately 41 kDa. It is expressed in various tissues with notable presence in muscle tissue and peripheral blood mononuclear cells.
Biological function summary

NT5C1A contributes to the regulation of nucleotide pools in cells impacting DNA and RNA synthesis and degradation processes. It functions independently and does not seem to be a part of a larger complex. Its activity ensures balanced nucleotide levels which is essential for proper cellular function and replication.

Pathways

NT5C1A participates in the purine metabolism pathway by influencing the concentration of nucleosides and nucleotides. It works in coordination with other enzymes such as adenosine deaminase and xanthine oxidase within these metabolic processes. NT5C1A's role is pivotal in maintaining nucleotide homeostasis during cellular proliferation and apoptosis.

NT5C1A has been linked to sporadic inclusion body myositis a muscle disorder characterized by muscle inflammation and weakening. Some studies suggest a connection with autoimmune diseases; however research is still evolving in this area. In these conditions NT5C1A interacts with proteins involved in immune response modulation hinting at its role in disease development.
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일반 정보

기능

Catalyzes the hydrolysis of ribonucleotide and deoxyribonucleotide monophosphates, releasing inorganic phosphate and the corresponding nucleoside (PubMed : 11133996, PubMed : 34814800, PubMed : 7599155, PubMed : 8967393). AMP is the major substrate but can also hydrolyze dCMP and IMP (PubMed : 11133996, PubMed : 34814800, PubMed : 7599155, PubMed : 8967393).

서열 유사성

Belongs to the 5'-nucleotidase type 3 family.

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제품 프로토콜

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타겟 정보

Catalyzes the hydrolysis of ribonucleotide and deoxyribonucleotide monophosphates, releasing inorganic phosphate and the corresponding nucleoside (PubMed : 11133996, PubMed : 34814800, PubMed : 7599155, PubMed : 8967393). AMP is the major substrate but can also hydrolyze dCMP and IMP (PubMed : 11133996, PubMed : 34814800, PubMed : 7599155, PubMed : 8967393).
See full target information Cytosolic 5'-nucleotidase 1A
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Product promise

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