Recombinant Human OIF protein (His tag) is a Human Full Length protein, in the 1 to 298 aa range, expressed in HEK 293 cells, with >95%, < 1 EU/µg endotoxin level, suitable for SDS-PAGE.
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OIF, SLRR3A, OGN, Mimecan, Osteoglycin, Osteoinductive factor
- SDS-PAGE
Supplier Data
SDS-PAGE - Recombinant Human OIF protein (His tag) (AB276546)
SDS-PAGE analysis of ab276546
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This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
Ovulation Inducing Factor acts as a signaling molecule that interacts with the female reproductive system to trigger ovulation. It functions as part of a larger biochemical complex that affects the hypothalamus and pituitary gland axis stimulating the secretion of hormones necessary for the release of the egg. The exact interactions and pathways remain an active area of research but the ability of OIF to prompt ovulation positions it as a unique factor among reproductive proteins.
Pathways
There is evidence that Ovulation Inducing Factor is involved in the neuroendocrine pathway for ovulation. OIF interacts with the hypothalamus-pituitary-gonadal axis to initiate ovulation. The presence of other proteins like GnRH and its release is closely tied to the activity of OIF in stimulating the necessary hormonal environment. Furthermore the interplay between OIF and luteinizing hormone (LH) is also explored showing how these elements integrate into the broader signaling cascade essential for ovulation.
일반 정보
기능
Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2.
서열 유사성
Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily.
Post-translational modifications
O-glycosylated with a core 1 or possibly core 8 glycan.. Contains keratan sulfate.
타겟 정보
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