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AB289768

Recombinant Human OR13A1 protein

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Recombinant Human OR13A1 protein is a Human Full Length protein, in the 1 to 328 aa range, expressed in Cell free, with >85%, suitable for SDS-PAGE.

대체 명칭 보기

Olfactory receptor 13A1, Olfactory receptor OR10-3, OR13A1

1 이미지
SDS-PAGE - Recombinant Human OR13A1 protein (AB289768)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human OR13A1 protein (AB289768)

SDS-PAGE analysis of ab289768

주요 정보

Purity

>85% SDS-PAGE

발현 시스템

Cell free

Tags

His tag N-Terminus

Applications

SDS-PAGE

applications

Biologically active

No

Accession

Animal free

Yes

Carrier free

No

Species

Human

보관 버퍼

pH: 7.4 - 8 Constituents: 6% Trehalose, 0.87% Sodium chloride, 0.24% Tris, 0.05% 2-Octadecoxyethanol

storage-buffer

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보완 제품

Reagents, Controls & Accessories

AB275754

pCambia1300 Plant Expression Vector

Vector - pCambia1300 Plant Expression Vector (AB275754)

  • 0
  • 0
Assay Kits

AB287846

Beta Galactosidase Assay Kit (Green)

Enzyme activity assay - Beta Galactosidase Assay Kit (Green) (AB287846)

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  • 0
Biochemicals

AB120487

Z-VAD(OMe)-FMK, Cell permeable, irreversible pan-caspase inhibitor

Functional Studies - Z-VAD(OMe)-FMK, Cell permeable, irreversible pan-caspase inhibitor (AB120487)

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Proteins & Peptides

AB276324

Recombinant Human HRG protein (His tag)

SDS-PAGE - Recombinant Human HRG protein (His tag) (AB276324)

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  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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서열 정보

[{"linker":null,"sequence":"MKLWMESHLIVPETRPSPRMMSNQTLVTEFILQGFSEHPEYRVFLFSCFLFLYSGALTGNVLITLAITFNPGLHAPMYFFLLNLATMDIICTSSIMPKALASLVSEESSISYGGCMAQLYFLTWAASSELLLLTVMAYDRYAAICHPLHYSSMMSKVFCSGLATAVWLLCAVNTAIHTGLMLRLDFCGPNVIIHFFCEVPPLLLLSCSSTYVNGVMIVLADAFYGIVNFLMTIASYGFIVSSILKVKTAWGRQKAFSTCSSHLTVVCMYYTAVFYAYISPVSGYSAGKSKLAGLLYTVLSPTLNPLIYTLRNKEVKAALRKLFPFFRN","proteinLength":"Full Length","predictedMolecularWeight":"39.3 kDa","actualMolecularWeight":null,"aminoAcidEnd":328,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Cell free","accessionNumber":"Q8NGR1","tags":[{"tag":"His","terminus":"N-Terminus"}]}]
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특성 및 보관 정보

제형
Lyophilized
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
False
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

OR13A1 also known as olfactory receptor 13A1 is a member of the large family of G-protein-coupled receptors (GPCRs). This protein plays an important role in detecting odor molecules as part of the olfactory system. It has a molecular mass of approximately 35 kDa. OR13A1 is expressed in the olfactory epithelium where olfactory receptors are located and is involved in initiating the neuronal responses that result in the perception of smell.
Biological function summary

OR13A1 participates in the detection and differentiation of odorants acting as a critical mediator in olfactory signal transduction. It functions by binding specific volatile molecules which triggers a conformational change activating an associated G-protein. This receptor does not work alone; it is an integral component of a receptor complex that collaborates in amplifying and processing olfactory signals.

Pathways

The olfactory receptor OR13A1 is part of the olfactory signaling pathway which is responsible for odor detection and transmission to the brain. This pathway involves the activation of adenylate cyclase through G-proteins leading to the synthesis of cyclic AMP which opens ion channels. This process is shared with other olfactory receptors including related GPCR proteins such as OR1A1 ensuring a consistent mechanism for odor signal transduction.

Alterations or dysfunction in OR13A1 may contribute to anosmia or hyposmia conditions characterized by the loss or reduction in the ability to smell. These conditions can result from genetic mutations or environmental factors affecting OR13A1. OR13A1 through its signaling pathway may also interact with other olfactory proteins like OR13C5 which might be implicated in such olfactory dysfunctions.
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일반 정보

기능

Odorant receptor.

서열 유사성

Belongs to the G-protein coupled receptor 1 family.

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제품 프로토콜

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타겟 정보

Odorant receptor.
See full target information OR13A1
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Product promise

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