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AB235615

Recombinant Human PHO1 protein (Tagged)

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Recombinant Human PHO1 protein (Tagged) is a Human Full Length protein, in the 1 to 199 aa range, expressed in Escherichia coli, with >90%, suitable for SDS-PAGE.

대체 명칭 보기

DNA dC->dU-editing enzyme APOBEC-3A, A3A, Phorbolin-1, APOBEC3A

1 이미지
SDS-PAGE - Recombinant Human PHO1 protein (Tagged) (AB235615)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human PHO1 protein (Tagged) (AB235615)

ab235615 analyzed by (Tris-Glycine gel) discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

주요 정보

Purity

>90% SDS-PAGE

발현 시스템

Escherichia coli

Tags

6x His tag N-Terminus SUMO tag N-Terminus

Applications

SDS-PAGE

applications

Biologically active

No

Accession

Animal free

No

Carrier free

No

Species

Human

보관 버퍼

pH: 7.2 - 7.4 Constituents: Tris buffer, 50% Glycerol (glycerin, glycerine)

storage-buffer

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보완 제품

Proteins & Peptides

AB160558

Recombinant Human APOBEC3B protein (GST tag N-Terminus)

SDS-PAGE - Recombinant Human APOBEC3B protein (GST tag N-Terminus) (AB160558)

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  • 0
Proteins & Peptides

AB313356

Recombinant Human IDO1 Protein (His tag) (E.Coli)

Mass Spectrometry - Recombinant Human IDO1 Protein (His tag) (E.Coli) (AB313356)

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  • 0
Primary Antibodies

AB184990

Anti-APOBEC3B antibody [EPR18138]

RabMAb|Recombinant

Western blot - Anti-APOBEC3B antibody [EPR18138] (AB184990)

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  • 3
Proteins & Peptides

AB158771

Recombinant Human ISG20 protein (GST tag N-Terminus)

SDS-PAGE - Recombinant Human ISG20 protein (GST tag N-Terminus) (AB158771)

  • 0
  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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서열 정보

[{"linker":null,"sequence":"MEASPASGPRHLMDPHIFTSNFNNGIGRHKTYLCYEVERLDNGTSVKMDQHRGFLHNQAKNLLCGFYGRHAELRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQENTHVRLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYDEFKHCWDTFVDHQGCPFQPWDGLDEHSQALSGRLRAILQNQGN","proteinLength":"Full Length","predictedMolecularWeight":"39 kDa","actualMolecularWeight":null,"aminoAcidEnd":199,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"P31941","tags":[{"tag":"6x His","terminus":"N-Terminus"},{"tag":"SUMO","terminus":"N-Terminus"}]}]
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특성 및 보관 정보

제형
Liquid
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
-20°C
적절한 장기 보관 조건
-20°C
보관 정보
Avoid freeze / thaw cycle
False
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

PHO1 also known as phosphate transporter 1 is a protein involved in the transport of phosphate across membranes. It has a molecular mass of approximately 86 kDa and is expressed significantly in the vascular tissues of plants especially in roots and shoots. This transporter functions by facilitating the efflux of phosphate into the xylem which enables the mobilization of phosphate from roots to aerial parts of the plant.
Biological function summary

PHO1 plays a critical role in maintaining phosphate homeostasis within the plant system. The protein works in coordination with other phosphate transport components as part of the phosphate transport complex. By regulating phosphate distribution PHO1 ensures optimal nutrient availability which is essential for various cellular and metabolic processes including energy transfer signaling and nucleic acid synthesis.

Pathways

PHO1 is an integral component of the phosphate signaling and homeostasis pathways. It interacts with proteins like PHR1 (Phosphate Starvation Response 1) which acts as a transcription factor that regulates the expression of phosphate-responsive genes. Additionally PHO1 plays a role in the systemic signaling pathway that links soil nutrient availability to shoot nutrient processes providing feedback for phosphate uptake from the environment.

PHO1 alterations relate to phosphate deficiency conditions which can impact plant growth and agriculture productivity. The protein's malfunction could lead to disorders in plants similar to nutritional deficiencies reducing crop yield and health. Interestingly similar pathways involve proteins like PHO2 that control phosphate uptake further demonstrating the interconnected network that PHO1 is part of in maintaining nutrient balance.
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일반 정보

기능

DNA deaminase (cytidine deaminase) with restriction activity against viruses, foreign DNA and mobility of retrotransposons. Exhibits antiviral activity against adeno-associated virus (AAV) and human T-cell leukemia virus type 1 (HTLV-1) and may inhibit the mobility of LTR and non-LTR retrotransposons. Selectively targets single-stranded DNA and can deaminate both methylcytosine and cytosine in foreign DNA. Can induce somatic hypermutation in the nuclear and mitochondrial DNA. May also play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation.

서열 유사성

Belongs to the cytidine and deoxycytidylate deaminase family.

Subcellular localisation

Nucleus

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제품 프로토콜

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타겟 정보

DNA deaminase (cytidine deaminase) with restriction activity against viruses, foreign DNA and mobility of retrotransposons. Exhibits antiviral activity against adeno-associated virus (AAV) and human T-cell leukemia virus type 1 (HTLV-1) and may inhibit the mobility of LTR and non-LTR retrotransposons. Selectively targets single-stranded DNA and can deaminate both methylcytosine and cytosine in foreign DNA. Can induce somatic hypermutation in the nuclear and mitochondrial DNA. May also play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation.
See full target information APOBEC3A
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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