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AB283430

Recombinant Human Prostate Specific Antigen protein

Recombinant Human Prostate Specific Antigen 단백질

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Recombinant Human Prostate Specific Antigen protein is a Human Full Length protein in the 25 to 261 aa range with >=95% purity, <= 0.005 EU/µg endotoxin level and suitable for SDS-PAGE, mass spectrometry and HPLC. The predicted molecular weight of ab283430 protein is 26.15 kDa.

- Save time and ensure accurate results - use our Human Prostate Specific Antigen (PSA) protein as a control
- Available in different sizes to fit your experimental needs

대체 명칭 보기

APS, KLK3, Prostate-specific antigen, PSA, Gamma-seminoprotein, Kallikrein-3, P-30 antigen, Semenogelase, Seminin

3 이미지
Mass Spectrometry - Recombinant Human Prostate Specific Antigen protein (AB283430)
  • Mass Spec

Supplier Data

Mass Spectrometry - Recombinant Human Prostate Specific Antigen protein (AB283430)

Mass determination by ESI-TOF.

Predicted MW is 26146.07 Da (+/- 10 Da by ESI-TOF). Observed MW is 26148.77

SDS-PAGE - Recombinant Human Prostate Specific Antigen protein (AB283430)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human Prostate Specific Antigen protein (AB283430)

SDS-page analysis of ab283430

HPLC - Recombinant Human Prostate Specific Antigen protein (AB283430)
  • HPLC

Supplier Data

HPLC - Recombinant Human Prostate Specific Antigen protein (AB283430)

HPLC analysis of ab283430

주요 정보

Purity

>95% HPLC

Endotoxin 레벨

<0.005 EU/µg

발현 시스템

HEK 293 cells

Tags

Tag free

Applications

HPLC, SDS-PAGE, Mass Spec

applications

Biologically active

No

Accession

Animal free

Yes

Carrier free

Yes

Species

Human

Reconstitution

Reconstitute in PBS

보관 버퍼

pH: 7.4 Constituents: 10.26% Trehalose, 0.727% Dibasic monohydrogen potassium phosphate, 0.248% Potassium phosphate monobasic

storage-buffer

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보완 제품

Reagents, Controls & Accessories

AB116029

Prestained Protein Ladder - Extra broad molecular weight (5 - 245 kDa)

SDS-PAGE - Prestained Protein Ladder - Extra broad molecular weight (5 - 245 kDa) (AB116029)

  • 5
  • 1
Primary Antibodies

AB76113

Anti-Prostate Specific Antigen antibody [EP1588Y]

BOND RX™ Validated|20ul selling size|RabMAb|Advanced Validation|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Prostate Specific Antigen antibody [EP1588Y] (AB76113)

  • 0
  • 0
Assay Kits

AB256313

Human/Monkey PSA Antibody Pair - BSA and Azide free

RabMAb|Recombinant

Sandwich ELISA - Human/Monkey PSA Antibody Pair - BSA and Azide free (AB256313)

  • 0
  • 0
Sample Prep & Detection Kits

AB201796

Biotinylation Kit / Biotin Conjugation Kit (Fast, Type B) - Lightning-Link®

Conjugation - Biotinylation Kit / Biotin Conjugation Kit (Fast, Type B) - Lightning-Link® (AB201796)

  • 3
  • 1
Assay Kits

AB264615

Human PSA ELISA Kit

Recombinant|SimpleStep

ELISA - Human PSA ELISA Kit (AB264615)

  • 0
  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "Mass Spec": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "HPLC": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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제품 세부 정보

Ensure the validity of your result using our recombinant human Prostate Specific Antigen (PSA)/ Kallikrein-3 protein ab283430 as a positive control in SDS-PAGE, mass spectrometry and HPLC.


Check out our protein gel staining guide for SDS-PAGE here
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서열 정보

[{"linker":null,"sequence":"IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVANP","proteinLength":"Full Length","predictedMolecularWeight":"26.15 kDa","actualMolecularWeight":null,"aminoAcidEnd":261,"aminoAcidStart":25,"nature":"Recombinant","expressionSystem":"HEK 293 cells","accessionNumber":"P07288","tags":[]}]
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특성 및 보관 정보

제형
Lyophilized
배송 시 보관 조건
Ambient - Can Ship with Ice
적절한 단기 보관 조건
Ambient
적절한 장기 보관 조건
Ambient
False
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

Prostate Specific Antigen (PSA) also known as kallikrein-related peptidase 3 (KLK3) is a serine protease with a mass of approximately 28.4 kDa. PSA is primarily expressed in the epithelial cells of the prostate gland. This glycoprotein is an important component in the seminal fluid where it performs its proteolytic activity that liquefies semen facilitating sperm motility.
Biological function summary

PSA functions by cleaving the gel-forming proteins present in seminal coagulum. It does not operate as part of a larger protein complex. PSA also interacts with substrates like fibronectin and semenogelin which play roles in seminal coagulation and liquefaction. The expression of PSA in prostate tissue has made it a valuable biomarker for prostate function and pathological conditions.

Pathways

PSA is involved in the kallikrein-kinin system which influences inflammation and blood pressure regulation. PSA is not directly a part of key metabolic or signaling pathways but it is co-expressed with key proteins like androgen receptor (AR) which modulates PSA's expression. The interplay between androgens and PSA highlights its role in hormone regulation within the male reproductive system.

PSA levels serve as an indicator for prostate cancer and benign prostatic hyperplasia (BPH). Elevated PSA levels often correlate with prostate cancer although other prostate conditions such as prostatitis can also increase PSA without cancer. Proteins like PCA3 and the AR are also connected in the context of prostate cancer providing a broader understanding of PSA's role in these diseases.
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일반 정보

기능

Hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum.

서열 유사성

Belongs to the peptidase S1 family. Kallikrein subfamily.

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제품 프로토콜

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타겟 정보

Hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum.
See full target information KLK3
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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