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AB160571

Recombinant Human RAB36 protein (GST tag N-Terminus)

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Recombinant Human RAB36 protein (GST tag N-Terminus) is a Human Full Length protein, in the 1 to 333 aa range, expressed in Wheat germ, suitable for ELISA, WB.

대체 명칭 보기

Ras-related protein Rab-36, RAB36

1 이미지
SDS-PAGE - Recombinant Human RAB36 protein (GST tag N-Terminus) (AB160571)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human RAB36 protein (GST tag N-Terminus) (AB160571)

ab160571 on a 12.5% SDS-PAGE stained with Coomassie Blue.

주요 정보

발현 시스템

Wheat germ

Tags

GST tag N-Terminus

Applications

ELISA, WB

applications

Biologically active

No

Accession

Animal free

No

Carrier free

No

Species

Human

보관 버퍼

pH: 8 Constituents: 0.79% Tris HCl, 0.31% Glutathione

storage-buffer

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보완 제품

Secondary Antibodies

AB150113

Goat Anti-Mouse IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Mouse IgG H&L (Alexa Fluor® 488) (AB150113)

  • 5
  • 16
Proteins & Peptides

AB159886

Recombinant Human ZP2 protein (GST tag N-Terminus)

SDS-PAGE - Recombinant Human ZP2 protein (GST tag N-Terminus) (AB159886)

  • 0
  • 0
Proteins & Peptides

AB162402

Recombinant Human Zinc finger protein 691 (GST tag N-Terminus)

SDS-PAGE - Recombinant Human Zinc finger protein 691 (GST tag N-Terminus) (AB162402)

  • 0
  • 0
Proteins & Peptides

AB161146

Recombinant Human BS69 protein (GST tag N-Terminus)

SDS-PAGE - Recombinant Human BS69 protein (GST tag N-Terminus) (AB161146)

  • 0
  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "ELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "WB": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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서열 정보

[{"linker":null,"sequence":"MVIAGASWMLGRAAASPTQTPPTTSTIRVARRSRVALVAMVIAAAGSGGPGRAEPQLSQPSLDCGRMRSSLTPLGPPVSRDRVIASFPKWYTPEACLQLREHFHGQVSAACQRRNTGTVGLKLSKVVVVGDLYVGKTSLIHRFCKNVFDRDYKATIGVDFEIERFEIAGIPYSLQIWDTAGQEKFKCIASAYYRGAQVIITAFDLTDVQTLEHTRQWLEDALRENEAGSCFIFLVGTKKDLLSGAACEQAEADAVHLAREMQAEYWSVSAKTGENVKAFFSRVAALAFEQSVLQDLERQSSARLQVGNGDLIQMEGSPPETQESKRPSSLGCC","proteinLength":"Full Length","predictedMolecularWeight":null,"actualMolecularWeight":null,"aminoAcidEnd":333,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Wheat germ","accessionNumber":"O95755","tags":[{"tag":"GST","terminus":"N-Terminus"}]}]
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Proprietary technique
배송 시 보관 조건
Dry Ice
적절한 단기 보관 조건
-80°C
적절한 장기 보관 조건
-80°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
False
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

RAB36 is a member of the RAS oncogene family and functions mechanically as a small GTPase a protein that binds and hydrolyzes guanosine triphosphate (GTP). It is often abbreviated as member RAS oncogene family 36 in literature. This protein has a molecular mass of approximately 35 kDa. RAB36 is expressed in various tissues including the brain where it plays a significant role in intracellular signaling and transport processes.
Biological function summary

RAB36 regulates intracellular vesicle trafficking which is essential for proper cellular function. It does this by controlling vesicle movement along cytoskeletal tracks and facilitating the fusion of vesicles with their target membranes. RAB36 operates independently not forming part of any known complex but it might interact with other proteins that contribute to the same biological processes in the cell.

Pathways

RAB36 participates in the regulation of membrane trafficking pathways which are fundamental for cellular homeostasis and communication. These pathways indicate its association with proteins such as RAB7 and RAB9 both of which are also part of the RAB family and share roles in vesicular transport. RAB36 is particularly addressed in exocytic pathways influencing the delivery of proteins and lipids to the cell surface.

Alterations in RAB36 expression or function can link to disorders of intracellular trafficking like neurodegenerative diseases and cancer. Incorrect vesicle transport and fusion may contribute to the pathology of these conditions. Additionally proteins like RAB7 which is associated with RAB36 also relate to similar disorders highlighting the importance of proper regulation of the RAB family in disease prevention.
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일반 정보

기능

The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion.

서열 유사성

Belongs to the small GTPase superfamily. Rab family.

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제품 프로토콜

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타겟 정보

The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion.
See full target information RAB36
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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