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AB109148

Recombinant Human RANK protein (Human IgG1 Fc tag C-Terminus)

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Recombinant Human RANK protein (Human IgG1 Fc tag C-Terminus) is a Human Fragment protein, in the 29 to 313 aa range, expressed in HEK 293 cells, with >95%, < 0.1 EU/µg endotoxin level, suitable for SDS-PAGE, FuncS.

주요 정보

Purity

>95% SDS-PAGE

Endotoxin 레벨

< 0.1 EU/µg

발현 시스템

HEK 293 cells

Tags

Human IgG1 Fc tag C-Terminus

Applications

FuncS, SDS-PAGE

applications

Biologically active

No

Accession

Q9Y6Q6-1

Animal free

No

Carrier free

No

Species

Human

Reconstitution

Reconstitute with 50µl sterile water to give a final concentration of 1mg/ml.

보관 버퍼

Constituents: PBS

storage-buffer

Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "FuncS": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }

제품 세부 정보

After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. PBS containing at least 0.1% BSA should be used for further dilutions. Inhibits Human rhsRANKL biological functions. Binds to Human and Mouse RANKL.

서열 정보

[{"linker":null,"sequence":"","proteinLength":"Fragment","predictedMolecularWeight":"55 kDa","actualMolecularWeight":null,"aminoAcidEnd":313,"aminoAcidStart":29,"nature":"Recombinant","expressionSystem":null,"accessionNumber":"Q9Y6Q6","tags":[{"tag":"Human IgG1 Fc","terminus":"C-Terminus"}]}]

특성 및 보관 정보

제형
Lyophilized
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
Up to 6 months
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
False

일반 정보

기능

Receptor for TNFSF11/RANKL/TRANCE/OPGL; essential for RANKL-mediated osteoclastogenesis (PubMed : 9878548). Its interaction with EEIG1 promotes osteoclastogenesis via facilitating the transcription of NFATC1 and activation of PLCG2 (By similarity). Involved in the regulation of interactions between T-cells and dendritic cells (By similarity).

제품 프로토콜

타겟 정보

Receptor for TNFSF11/RANKL/TRANCE/OPGL; essential for RANKL-mediated osteoclastogenesis (PubMed : 9878548). Its interaction with EEIG1 promotes osteoclastogenesis via facilitating the transcription of NFATC1 and activation of PLCG2 (By similarity). Involved in the regulation of interactions between T-cells and dendritic cells (By similarity).
See full target information TNFRSF11A

대체 명칭 보기

CD265, RANK, TNFRSF11A, Tumor necrosis factor receptor superfamily member 11A, Osteoclast differentiation factor receptor, Receptor activator of NF-KB, ODFR

Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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