Recombinant Human RANK protein (His tag) is a Human Fragment protein, in the 28 to 202 aa range, expressed in Escherichia coli, with >90%, suitable for SDS-PAGE.
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CD265, RANK, TNFRSF11A, Tumor necrosis factor receptor superfamily member 11A, Osteoclast differentiation factor receptor, Receptor activator of NF-KB, ODFR
- SDS-PAGE
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SDS-PAGE - Recombinant Human RANK protein (His tag) (AB240776)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel analysis of ab240776.
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기능
Receptor for TNFSF11/RANKL/TRANCE/OPGL; essential for RANKL-mediated osteoclastogenesis (PubMed : 9878548). Its interaction with EEIG1 promotes osteoclastogenesis via facilitating the transcription of NFATC1 and activation of PLCG2 (By similarity). Involved in the regulation of interactions between T-cells and dendritic cells (By similarity).
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