AB153634

Recombinant Human RNase H1/RNH1 protein (GST tag N-Terminus)

(1 Review)

(6 Publications)

Recombinant Human RNase H1/RNH1 protein (GST tag N-Terminus) is a Human Full Length protein, in the 1 to 286 aa range, expressed in Wheat germ, with >80%, suitable for SDS-PAGE, ELISA, WB.

대체 명칭 보기

RNH1, RNASEH1, Ribonuclease H1, RNase H1, Ribonuclease H type II

1 Images

SDS-PAGE - Recombinant Human RNase H1/RNH1 protein (GST tag N-Terminus) (AB153634)

SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human RNase H1/RNH1 protein (GST tag N-Terminus) (AB153634)

ab153634 on a 12.5% SDS-PAGE stained with Coomassie Blue.

주요 정보

Purity

>80%

Glutathione Sepharose 4 Fast Flow

발현 시스템

Wheat germ

Applications

ELISA, SDS-PAGE, WB

applications

Biologically active

Accession

O60930

Animal free

Carrier free

Species

Human

보관 버퍼

pH: 8 Constituents: 0.79% Tris HCl, 0.31% Glutathione

storage-buffer

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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"" }, "ELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"" }, "WB": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"" } } }

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제품 세부 정보

Protein concentration is above or equal to 0.03 mg/ml.

This product was previously labelled as RNase H1

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서열 정보

[{"sequence":"MSWLLFLAHRVALAALPCRRGSRGFGMFYAVRRGRKTGVFLTWNECRAQVDRFPAARFKKFATEDEAWAFVRKSASPEVSEGHENQHGQESEAKASKRLREPLDGDGHESAEPYAKHMKPSVEPAPPVSRDTFSYMGDFVVVYTDGCCSSNGRRRPRAGIGVYWGPGHPLNVGIRLPGRQTNQRAEIHAACKAIEQAKTQNINKLVLYTDSMFTINGITNWVQGWKKNGWKTSAGKEVINKEDFVALERLTQGMDIQWMHVPGHSGFIGNEEADRLAREGAKQSED","proteinLength":"Full Length","predictedMolecularWeight":"58.5 kDa","actualMolecularWeight":null,"aminoAcidEnd":286,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Wheat germ","accessionNumber":"O60930","tags":[{"tag":"GST","terminus":"N-Terminus"}]}]

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특성 및 보관 정보

제형

Liquid

Purification 테크닉

Affinity purification GST Tag

배송 시 보관 조건

Dry Ice

적절한 단기 보관 조건

-80°C

적절한 장기 보관 조건

-80°C

분주 정보

Upon delivery aliquot

보관 정보

Avoid freeze / thaw cycle

False

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일반 정보

기능

Endonuclease that specifically degrades the RNA of RNA-DNA hybrids (PubMed : 10497183). Plays a role in RNA polymerase II (RNAp II) transcription termination by degrading R-loop RNA-DNA hybrid formation at G-rich pause sites located downstream of the poly(A) site and behind the elongating RNAp II (PubMed : 21700224).

서열 유사성

Belongs to the RNase H family.

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제품 프로토콜

Visit the General protocols
Visit the Troubleshooting

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타겟 정보

See full target information RNASEH1

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제품이 사용된 논문 (6)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Molecular therapy. Nucleic acids 36:102404 PubMed39759873

2025

Discovery and characterization of stereodefined PMO-gapmers targeting tau.

Applications

Unspecified application

Species

Unspecified reactive species

Kunihiko Kanatsu,Yoshinori Takahashi,Tetsuya Sakaguchi,Dae-Shik Kim,Miki Murota,Mingde Shan,Kazuki Fukami,Wataru Itano,Kenji Kikuta,Hikaru Yoshimura,Toshiki Kurokawa,Yuko Nagayama,Rena Ishikawa,Ryo Dairiki,Zhi Zhou,Kristen Sanders,Jacob Stupalski,So Yasui,Diana Liu,Farid Benayoud,Hui Fang,Enxuan Jing,Makoto Ogo,Francis G Fang,John Wang,Hyeong-Wook Choi

iScience 27:109797 PubMed38993671

2024

Bromodomain protein BRD4 directs mitotic cell division of mouse fibroblasts by inhibiting DNA damage.

Applications

Unspecified application

Species

Unspecified reactive species

Tiyun Wu,Haitong Hou,Anup Dey,Mahesh Bachu,Xiongfong Chen,Jan Wisniewski,Fuki Kudoh,Chao Chen,Sakshi Chauhan,Hua Xiao,Richard Pan,Keiko Ozato

Nature communications 14:8021 PubMed38049398

2023

JUN upregulation drives aberrant transposable element mobilization, associated innate immune response, and impaired neurogenesis in Alzheimer's disease.

Applications

Unspecified application

Species

Unspecified reactive species

Chiara Scopa,Samantha M Barnada,Maria E Cicardi,Mo Singer,Davide Trotti,Marco Trizzino

Nature communications 14:2413 PubMed37105964

2023

Chemical evolution of an autonomous DNAzyme with allele-specific gene silencing activity.

Applications

Unspecified application

Species

Unspecified reactive species

Kim Nguyen,Turnee N Malik,John C Chaput

Organic & biomolecular chemistry 20:8243-8258 PubMed36222332

2022

Synthesis and properties of oligodiaminogalactoses that bind to A-type oligonucleotide duplexes.

Applications

Unspecified application

Species

Unspecified reactive species

Tomomi Shiraishi,Kazuki Sato,Rintaro Iwata Hara,Takeshi Wada

Nature communications 12:1654 PubMed33712600

2021

ADAR1 RNA editing enzyme regulates R-loop formation and genome stability at telomeres in cancer cells.

Applications

Unspecified application

Species

Unspecified reactive species

Yusuke Shiromoto,Masayuki Sakurai,Moeko Minakuchi,Kentaro Ariyoshi,Kazuko Nishikura

제품이 사용된 논문 모두 보기

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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.

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Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Recombinant Human RNase H1/RNH1 protein (GST tag N-Terminus)

SDS-PAGE - Recombinant Human RNase H1/RNH1 protein (GST tag N-Terminus) (AB153634)

주요 정보

Purity

발현 시스템

Tags

Applications

Biologically active

Accession

Animal free

Carrier free

Species

보관 버퍼

보완 제품

Reagents, Controls & Accessories

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Reactivity 정보

제품 세부 정보

서열 정보

특성 및 보관 정보

제형

Purification 테크닉

배송 시 보관 조건

적절한 단기 보관 조건

적절한 장기 보관 조건

분주 정보

보관 정보

일반 정보

기능

서열 유사성

제품 프로토콜

타겟 정보

제품이 사용된 논문 (6)

Product promise