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AB290054

Recombinant Human ROR1 Protein

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Recombinant Human ROR1 Protein is a Human Fragment protein, in the 30 to 406 aa range, expressed in HEK 293 cells, with >95%, <0.005 EU/µg endotoxin level.

대체 명칭 보기

NTRKR1, ROR1, Inactive tyrosine-protein kinase transmembrane receptor ROR1

3 Images
Mass Spectrometry - Recombinant Human ROR1 Protein (AB290054)
  • Mass Spec

Supplier Data

Mass Spectrometry - Recombinant Human ROR1 Protein (AB290054)

Mass determination by ESI-TOF.

Predicted MW is 42434.71 Da. (+/- 10 Da by ESI-TOF). Observed MW is 42439.50 Da.

SDS-PAGE - Recombinant Human ROR1 Protein (AB290054)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human ROR1 Protein (AB290054)

SDS-PAGE analysis of ab290054

HPLC - Recombinant Human ROR1 Protein (AB290054)
  • HPLC

Supplier Data

HPLC - Recombinant Human ROR1 Protein (AB290054)

HPLC analysis of ab290054

주요 정보

Purity

>95% HPLC

Endotoxin 레벨

<0.005 EU/µg

발현 시스템

HEK 293 cells

Tags

Tag free

Biologically active

No

Accession

Q01973

Animal free

No

Carrier free

No

Species

Human

Reconstitution

Reconstitute in PBS

보관 버퍼

pH: 7.4 Constituents: 10.26% Trehalose, 0.727% Dibasic monohydrogen potassium phosphate, 0.248% Potassium phosphate monobasic

storage-buffer

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보완 제품

Primary Antibodies

AB280197

Anti-ROR1 antibody [EPR24451-141]

20ul selling size|RabMAb|Recombinant

Flow Cytometry (Intracellular) - Anti-ROR1 antibody [EPR24451-141] (AB280197)

  • 0
  • 0
Secondary Antibodies

AB150077

Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (AB150077)

  • 5
  • 20
Primary Antibodies

AB9485

Anti-GAPDH antibody - Loading Control

BOND RX™ Validated|Lab Essentials

Immunocytochemistry/ Immunofluorescence - Anti-GAPDH antibody - Loading Control (AB9485)

  • 5
  • 88
Assay Kits

AB289641

Human ROR1 ELISA Kit

Recombinant|SimpleStep

Sandwich ELISA - Human ROR1 ELISA Kit (AB289641)

  • 0
  • 0
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서열 정보

[{"linker":null,"sequence":"QETELSVSAELVPTSSWNISSELNKDSYLTLDEPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQCVATNGKEVVSSTGVLFVKFGPPPTASPGYSDEYEEDGFCQPYRGIACARFIGNRTVYMESLHMQGEIENQITAAFTMIGTSSHLSDKCSQFAIPSLCHYAFPYCDETSSVPKPRDLCRDECEILENVLCQTEYIFARSNPMILMRLKLPNCEDLPQPESPEAANCIRIGIPMADPINKNHKCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHSYCRNPGNQKEAPWCFTLDENFKSDLCDIPACDSKDSKEKNKMEILY","proteinLength":"Fragment","predictedMolecularWeight":null,"actualMolecularWeight":null,"aminoAcidEnd":406,"aminoAcidStart":30,"nature":"Recombinant","expressionSystem":null,"accessionNumber":"Q01973","tags":[]}]
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특성 및 보관 정보

제형
Lyophilized
배송 시 보관 조건
Ambient - Can Ship with Ice
적절한 단기 보관 조건
-20°C
적절한 장기 보관 조건
-20°C
False
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일반 정보

기능

Has very low kinase activity in vitro and is unlikely to function as a tyrosine kinase in vivo (PubMed : 25029443). Receptor for ligand WNT5A which activate downstream NFkB signaling pathway and may result in the inhibition of WNT3A-mediated signaling (PubMed : 25029443, PubMed : 27162350). In inner ear, crucial for spiral ganglion neurons to innervate auditory hair cells (PubMed : 27162350). Via IGFBP5 ligand, forms a complex with ERBB2 to enhance CREB oncogenic signaling (PubMed : 36949068).

서열 유사성

Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.

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제품 프로토콜

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타겟 정보

Has very low kinase activity in vitro and is unlikely to function as a tyrosine kinase in vivo (PubMed : 25029443). Receptor for ligand WNT5A which activate downstream NFkB signaling pathway and may result in the inhibition of WNT3A-mediated signaling (PubMed : 25029443, PubMed : 27162350). In inner ear, crucial for spiral ganglion neurons to innervate auditory hair cells (PubMed : 27162350). Via IGFBP5 ligand, forms a complex with ERBB2 to enhance CREB oncogenic signaling (PubMed : 36949068).
See full target information ROR1
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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