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AB156963

Recombinant Human SURF2 protein (His tag N-Terminus)

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Recombinant Human SURF2 protein (His tag N-Terminus) is a Human Full Length protein, in the 1 to 256 aa range, expressed in Escherichia coli, with >90%, suitable for SDS-PAGE, Mass Spec.

대체 명칭 보기

Surfeit locus protein 2, Surf-2, SURF2

1 이미지
SDS-PAGE - Recombinant Human SURF2 protein (His tag N-Terminus) (AB156963)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human SURF2 protein (His tag N-Terminus) (AB156963)

15% SDS-PAGE analysis of ab156963 (3 µg).

주요 정보

Purity

>90% SDS-PAGE

ab156963 was purified using conventional chromatography techniques.

발현 시스템

Escherichia coli

Tags

His tag N-Terminus

Applications

Mass Spec, SDS-PAGE

applications

Biologically active

No

Accession

Animal free

No

Carrier free

No

Species

Human

보관 버퍼

pH: 8 Constituents: 50% Glycerol (glycerin, glycerine), 1.17% Sodium chloride, 0.32% Tris HCl, 0.04% (R*,R*)-1,4-Dimercaptobutan-2,3-diol

storage-buffer

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보완 제품

Secondary Antibodies

AB97260

Goat Anti-Mouse IgG3 heavy chain (HRP)

  • 0
  • 0
Secondary Antibodies

AB207995

Goat Anti-Rabbit IgG H&L (Biotin)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Goat Anti-Rabbit IgG H&L (Biotin) (AB207995)

  • 0
  • 0
Secondary Antibodies

AB97235

Goat Anti-Mouse IgA alpha chain (HRP)

  • 0
  • 0
Secondary Antibodies

AB96947

Goat Anti-Chicken IgY H&L (DyLight® 488)

  • 5
  • 1
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "Mass Spec": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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서열 정보

[{"linker":null,"sequence":"MGSSHHHHHHSSGLVPRGSHMGSMSELPGDVRAFLREHPSLRLQTDARKVRCILTGHELPCRLPELQVYTRGKKYQRLVRASPAFDYAEFEPHIVPSTKNPHQLFCKLTLRHINKCPEHVLRHTQGRRYQRALCKYEECQKQGVEYVPACLVHRRRRREDQMDGDGPRPREAFWEPTSSDEGGAASDDSMTDLYPPELFTRKDLGSTEDGDGTDDFLTDKEDEKAKPPREKATDEGRRETTVYRGLVQKRGKKQLGSLKKKFKSHHRKPKSFSSCKQPG","proteinLength":"Full Length","predictedMolecularWeight":"32 kDa","actualMolecularWeight":null,"aminoAcidEnd":256,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"Q15527","tags":[{"tag":"His","terminus":"N-Terminus"}]}]
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특성 및 보관 정보

제형
Liquid
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
False
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

SURF2 also known as Surfeit 2 is a protein with an approximate mass of 28 kDa. It is a component of the surfeit gene cluster which is compact and does not include any common regulatory elements shared by its member genes. SURF2 is expressed in various tissues but has significant expression in the lung and kidney. The protein itself functions as part of the cellular machinery specifically in membrane trafficking though detailed mechanisms at the molecular level require further study.
Biological function summary

This protein is engaged in critical cellular processes such as the modulation of intracellular trafficking. SURF2 is associated with the endoplasmic reticulum and Golgi apparatus hinting at a role in vesicle movement between these organelles. It works in conjunction with other proteins like CLIMP-63 and Ergic-53 participating in the correct sorting and dispatching of cargo proteins.

Pathways

SURF2 functions as a cog within the ER-Golgi transport pathway. It ensures effective vesicular trafficking which is essential for protein processing and secretion. Proteins such as Rab1 and Sec23 relate to SURF2 by collaborating in maintaining the integrity and functionality of this transport mechanism. These pathways are fundamental for cellular homeostasis and protein quality control.

SURF2 exhibits potential links to certain respiratory diseases due to its expression profile in lung tissue. Researchers hypothesize that improper function or expression of SURF2 could influence conditions like chronic obstructive pulmonary disease (COPD). Furthermore connections between SURF2 and other proteins like alpha-1-antitrypsin indicate a potential involvement in conditions where protease inhibitor imbalance plays a critical role. Understanding these associations might help develop therapeutic strategies targeting these pathways.
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일반 정보

서열 유사성

Belongs to the SURF2 family.

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제품 프로토콜

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타겟 정보

See full target information SURF2
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Product promise

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