Recombinant Human TC-2 protein (His tag)

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This supplementary information is collated from multiple sources and compiled automatically.

Biological function summary

This protein facilitates the assembly of transcriptional pre-initiation complexes. TC-2 serves as a scaffolding component connecting different transcription factors and RNA polymerase II essential for gene initiation. It operates as part of a larger multi-protein complex which synchronizes the gene transcription process integrating signals that impact gene expression.

Pathways

TC-2 interacts extensively with gene regulation pathways such as the RNA polymerase II transcription pathway and the nuclear receptor signaling pathway. It is closely related to the protein transcription factor TBP in these pathways coordinating the transcription initiation process. These interactions highlight TC-2's role in the orchestration of gene expression through precise pathway integrations.