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AB276621

Recombinant Human TMIGD1 protein (His tag)

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Recombinant Human TMIGD1 protein (His tag) is a Human Fragment protein, in the 1 to 220 aa range, expressed in HEK 293 cells, with >95%, < 1 EU/µg endotoxin level, suitable for SDS-PAGE.

대체 명칭 보기

TMIGD, UNQ9372/PRO34164, TMIGD1, Transmembrane and immunoglobulin domain-containing protein 1

1 이미지
SDS-PAGE - Recombinant Human TMIGD1 protein (His tag) (AB276621)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human TMIGD1 protein (His tag) (AB276621)

SDS-PAGE analysis of ab276621

주요 정보

Purity

>95% SDS-PAGE

Endotoxin 레벨

< 1 EU/µg

발현 시스템

HEK 293 cells

Tags

His tag C-Terminus

Applications

SDS-PAGE

applications

Biologically active

No

Accession

Animal free

No

Carrier free

No

Species

Human

보관 버퍼

pH: 7.4 Constituents: PBS

storage-buffer

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보완 제품

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SDS-PAGE - Recombinant Human GFPT1 protein (GST tag N-Terminus) (AB152423)

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AB104668

Recombinant Human hnRNP C1/C2 protein (His tag N-Terminus)

SDS-PAGE - Recombinant Human hnRNP C1/C2 protein (His tag N-Terminus) (AB104668)

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SDS-PAGE - Recombinant Human CYP11A1 protein (GST tag N-Terminus) (AB132669)

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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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서열 정보

[{"linker":null,"sequence":"MAWKSSVIMQMGRFLLLVILFLPREMTSSVLTVNGKTENYILDTTPGSQASLICAVQNHTREEELLWYREEGRVDLKSGNKINSSSVCVSSISENDNGISFTCRLGRDQSVSVSVVLNVTFPPLLSGNDFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIVKDKTVGVP","proteinLength":"Fragment","predictedMolecularWeight":"22.6 kDa","actualMolecularWeight":null,"aminoAcidEnd":220,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"HEK 293 cells","accessionNumber":"Q6UXZ0","tags":[{"tag":"His","terminus":"C-Terminus"}]}]
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특성 및 보관 정보

제형
Lyophilized
배송 시 보관 조건
Ambient - Can Ship with Ice
적절한 단기 보관 조건
-20°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
False
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

TMIGD1 also known as Transmembrane and Immunoglobulin Domain Containing Protein 1 has a mass of approximately 34 kDa. This protein is localized to the plasma membrane and exhibits high expression in renal tissues including kidney epithelial cells. TMIGD1 may act as a cell surface receptor playing roles in cellular adhesion and signal transduction processes. Its structure involves an immunoglobulin-like domain suggesting a function in mediating interactions between cells or with the extracellular matrix.
Biological function summary

TMIGD1 contributes to maintaining cell integrity and supporting epithelial cell adherence. It seems to be involved in forming complexes with other cellular receptors or proteins that facilitate these cellular functions. This interaction is important for maintaining tissue structure and cellular communication within the renal system. Disruptions in TMIGD1 activity could lead to impaired cell adhesion and structural disarray.

Pathways

TMIGD1 shows involvement in pathways linked to cell adhesion and signal transduction. It collaborates with proteins like integrins and cadherins which are key players in the cellular adhesion machinery. Through these interactions TMIGD1 influences pathways that are important for cellular communication and adhesion directly impacting epithelial cell stability and kidney function.

TMIGD1 has shown associations with kidney-related conditions particularly renal carcinomas. Disruptions or mutations in TMIGD1 could interfere with normal kidney epithelial cell function contributing to the progression of renal cancer. Furthermore its relationship with integrins in this context points to its role in maintaining cellular adhesion which when compromised can influence cancer metastasis and progression.
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일반 정보

기능

May control cell-cell adhesion, cell migration and proliferation, cell morphology, and protects renal epithelial cells from oxidative cell injury to promote cell survival.

Post-translational modifications

N-glycosylated.

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제품 프로토콜

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타겟 정보

May control cell-cell adhesion, cell migration and proliferation, cell morphology, and protects renal epithelial cells from oxidative cell injury to promote cell survival.
See full target information TMIGD1
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Product promise

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