Recombinant Human TRP14 protein (His tag N-Terminus)
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Recombinant Human TRP14 protein (His tag N-Terminus) is a Human Full Length protein, in the 1 to 123 aa range, expressed in Escherichia coli, with >95%, suitable for SDS-PAGE, Mass Spec.
대체 명칭 보기
TXNL5, TXNDC17, Thioredoxin domain-containing protein 17, 14 kDa thioredoxin-related protein, Protein 42-9-9, Thioredoxin-like protein 5, TRP14
- SDS-PAGE
Unknown
SDS-PAGE - Recombinant Human TRP14 protein (His tag N-Terminus) (AB124598)
15% SDS-PAGE showing ab124598 (3µg).
보완 제품
Reactivity 정보
제품 세부 정보
서열 정보
특성 및 보관 정보
제형
배송 시 보관 조건
적절한 단기 보관 기간
적절한 단기 보관 조건
적절한 장기 보관 조건
분주 정보
보관 정보
추가 정보
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
TRP14 impacts the cellular reduction-oxidation state participating in processes of cell growth and defense against oxidative stress. It does not typically form part of larger protein complexes but instead acts independently within the cell to exert its function. Through its catalytic activity TRP14 influences signaling events that dictate cellular response to harmful oxidative conditions.
Pathways
TRP14 integrates into the thioredoxin system which regulates redox-sensitive signaling pathways. These pathways involve proteins such as TRP32 and thioredoxin. The activity of TRP14 also contributes to the oxidative stress response pathway affecting the activation of downstream targets like Nrf2 a transcription factor that mediates antioxidant defense.
일반 정보
기능
Disulfide reductase. May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions. Modulates TNF signaling and NF-kappa-B activation. Has peroxidase activity and may contribute to the elimination of cellular hydrogen peroxide.
서열 유사성
Belongs to the thioredoxin family.
Post-translational modifications
The oxidized protein is reduced by TRXR1.
타겟 정보
Product promise
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