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AB236178

Recombinant Human Versican protein (Tagged)

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(1 출판물)

Recombinant Human Versican protein (Tagged) is a Human Fragment protein, in the 3089 to 3354 aa range, expressed in Escherichia coli, with >85%, suitable for SDS-PAGE.

대체 명칭 보기

CSPG2, VCAN, Versican core protein, Chondroitin sulfate proteoglycan core protein 2, Glial hyaluronate-binding protein, Large fibroblast proteoglycan, PG-M, Chondroitin sulfate proteoglycan 2, GHAP

1 이미지
SDS-PAGE - Recombinant Human Versican protein (Tagged) (AB236178)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human Versican protein (Tagged) (AB236178)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel analysis of ab236178.

주요 정보

Purity

>85% SDS-PAGE

발현 시스템

Escherichia coli

Tags

10x His tag N-Terminus B2M tag N-Terminus Myc tag C-Terminus

Applications

SDS-PAGE

applications

Biologically active

No

Accession

Animal free

No

Carrier free

No

Species

Human

보관 버퍼

pH: 7.2 - 7.4 Constituents: Tris buffer, 50% Glycerol (glycerin, glycerine)

storage-buffer

Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }

서열 정보

[{"linker":null,"sequence":"GPDRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFRCLCLPSYVGALCEQDTETCDYGWHKFQGQCYKYFAHRRTWDAAERECRLQGAHLTSILSHEEQMFVNRVGHDYQWIGLNDKMFEHDFRWTDGSTLQYENWRPNQPDSFFSAGEDCVVIIWHENGQWNDVPCNYHLTYTCKKGTVACGQPPVVENAKTFGKMKPRYEINSLIRYHCKDGFIQRHLPTIRCLGNGRWAIPKITCMN","proteinLength":"Fragment","predictedMolecularWeight":"47.6 kDa","actualMolecularWeight":null,"aminoAcidEnd":3354,"aminoAcidStart":3089,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"P13611","tags":[{"tag":"10x His","terminus":"N-Terminus"},{"tag":"B2M","terminus":"N-Terminus"},{"tag":"Myc","terminus":"C-Terminus"}]}]

특성 및 보관 정보

제형
Liquid
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
-20°C
적절한 장기 보관 조건
-20°C
보관 정보
Avoid freeze / thaw cycle
False

일반 정보

기능

May play a role in intercellular signaling and in connecting cells with the extracellular matrix. May take part in the regulation of cell motility, growth and differentiation. Binds hyaluronic acid.

서열 유사성

Belongs to the aggrecan/versican proteoglycan family.

Post-translational modifications

Phosphorylated by FAM20C in the extracellular medium.. Proteolytically cleaved by ADAMTS5 and ADAMTS15 in the pericellular matrix surrounding myoblasts, facilitating myoblast contact and fusion which is required for skeletal muscle development and regeneration.

제품 프로토콜

타겟 정보

May play a role in intercellular signaling and in connecting cells with the extracellular matrix. May take part in the regulation of cell motility, growth and differentiation. Binds hyaluronic acid.
See full target information VCAN

제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

The Journal of biological chemistry 300:107968 PubMed39510178

2024

Versican binds collagen via its G3 domain and regulates the organization and mechanics of collagenous matrices.

Applications

Unspecified application

Species

Unspecified reactive species

Dongning Chen,Yu Du,Jessica Llewellyn,Arkadiusz Bonna,Biao Zuo,Paul A Janmey,Richard W Farndale,Rebecca G Wells
제품이 사용된 논문 모두 보기

Product promise

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