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AB165455

Recombinant Human ZNF358 protein (GST tag N-Terminus)

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Recombinant Human ZNF358 protein (GST tag N-Terminus) is a Human Full Length protein, in the 1 to 481 aa range, expressed in Wheat germ, suitable for ELISA, WB.

대체 명칭 보기

Zinc finger protein 358, ZNF358

1 이미지
SDS-PAGE - Recombinant Human ZNF358 protein (GST tag N-Terminus) (AB165455)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human ZNF358 protein (GST tag N-Terminus) (AB165455)

ab165455 on a 12.5% SDS-PAGE stained with Coomassie Blue.

주요 정보

발현 시스템

Wheat germ

Tags

GST tag N-Terminus

Applications

WB, ELISA

applications

Biologically active

No

Accession

Animal free

No

Carrier free

No

Species

Human

보관 버퍼

pH: 8 Constituents: 0.79% Tris HCl, 0.31% Glutathione

storage-buffer

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보완 제품

Primary Antibodies

AB2787

Anti-Hsp70 antibody [5A5]

Immunocytochemistry/ Immunofluorescence - Anti-Hsp70 antibody [5A5] (AB2787)

  • 5
  • 18
Primary Antibodies

AB202554

Anti-COX IV antibody [EPR9442(ABC)] - Mitochondrial Loading Control

RabMAb|Recombinant|Lab Essentials|Advanced Validation|20ul selling size

Multiplex immunohistochemistry - Anti-COX IV antibody [EPR9442(ABC)] - Mitochondrial Loading Control (AB202554)

  • 5
  • 2
Primary Antibodies

AB219644

Anti-Calnexin antibody - C-terminal

Immunocytochemistry/ Immunofluorescence - Anti-Calnexin antibody - C-terminal (AB219644)

  • 0
  • 0
Primary Antibodies

AB179826

Anti-TOMM22/TOM22 antibody [EPR13505] - N-terminal

20ul selling size|RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TOMM22/TOM22 antibody [EPR13505] - N-terminal (AB179826)

  • 0
  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "ELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "WB": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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서열 정보

[{"linker":null,"sequence":"MSSSFDLDPDVIGPVPLILDPNSDTLSPGDPKVDPISSGLTATPQVLATSPAVLPAPASPPRPFSCPDCGRAFRRSSGLSQHRRTHSGEKPYRCPDCGKSFSHGATLAQHRGIHTGARPYQCAACGKAFGWRSTLLKHRSSHSGEKPHHCPVCGKAFGHGSLLAQHLRTHGGPRPHKCPVCAKGFGQGSALLKHLRTHTGERPYPCPQCGKAFGQSSALLQHQRTHTAERPYRCPHCGKAFGQSSNLQHHLRIHTGERPYACPHCSKAFGQSSALLQHLHVHSGERPYRCQLCGKAFGQASSLTKHKRVHEGAAAAAAAAAAAAAAAAAGLGLGPGLSPASMMRPGQVSLLGPDAVSVLGSGLGLSPGTSSGRNPDPGSGPGTLPDPSSKPLPGSRSTPSPTPVESSDPKAGHDAGPDLVPSPDLDPVPSPDPDPVPSPDPNPVSCPDPCSPTRGTVSPALPTGESPEWVQEQGALLGPDG","proteinLength":"Full Length","predictedMolecularWeight":null,"actualMolecularWeight":null,"aminoAcidEnd":481,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Wheat germ","accessionNumber":"Q9NW07","tags":[{"tag":"GST","terminus":"N-Terminus"}]}]
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Proprietary technique
배송 시 보관 조건
Dry Ice
적절한 단기 보관 조건
-80°C
적절한 장기 보관 조건
-80°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
False
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

ZNF358 also known as ZFP358 is a zinc finger protein playing a role in gene transcription regulation. It has a molecular mass of approximately 85 kDa. This protein is known to bind DNA in a sequence-specific manner using the zinc finger motifs to function as a transcription factor. ZNF358 expression occurs in multiple tissues with research indicating significant levels in the brain and heart. The protein's mechanical action involves modulating the transcription of specific genes impacting various biological processes.
Biological function summary

ZNF358 modulates critical processes in cellular differentiation and development. As a member of the transcription factor family ZNF358 does not form part of a known multi-protein complex. Instead it functions independently influencing the transcription of genes involved in cellular responses and structural development. This protein plays a role in maintaining cellular homeostasis affecting developmental stages by activating or repressing target gene transcription.

Pathways

ZNF358 influences several notably the Wnt signaling pathway and the Notch signaling pathway. In the Wnt signaling pathway ZNF358 interacts with proteins involved in cellular growth and differentiation such as β-catenin. This pathway plays a significant role in embryonic development and tissue regeneration. In relation to Notch signaling ZNF358 interacts with pathway components influencing cell fate determination and neural development collaborating with proteins like Notch receptors.

ZNF358 shows associations with developmental disorders particularly related to neural and cardiac malformations. Aberrant expression or dysfunction of ZNF358 may contribute to conditions like congenital heart defects due to its impact on cardiac development genes. Additionally disrupted ZNF358 function has links to neurodevelopmental disorders influencing neural pathway genes. Any interactions leading to disease often involve other transcription factors that interact with this protein in the developmental pathways.
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일반 정보

기능

May be involved in transcriptional regulation.

서열 유사성

Belongs to the krueppel C2H2-type zinc-finger protein family.

Subcellular localisation

Nucleus

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제품 프로토콜

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타겟 정보

May be involved in transcriptional regulation.
See full target information ZNF358
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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