Recombinant Mouse CDCP1 protein (His tag) is a Mouse Fragment protein, in the 1 to 666 aa range, expressed in HEK 293 cells, with >96%, < 1 EU/µg endotoxin level, suitable for SDS-PAGE.
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CD318, CUB domain-containing protein 1, Membrane glycoprotein gp140, Transmembrane and associated with src kinases, Cdcp1
- SDS-PAGE
Supplier Data
SDS-PAGE - Recombinant Mouse CDCP1 protein (His tag) (AB276981)
SDS-PAGE analysis of ab276981
보완 제품
Primary Antibodies
AB259686
Anti-CDCP1 antibody [EPR22487-51] - BSA and Azide free (Detector)
RabMAb|Recombinant
![Sandwich ELISA - Anti-CDCP1 antibody [EPR22487-51] - BSA and Azide free (Detector) (AB259686)](https://content.abcam.com/products/images/cdcp1-antibody-epr22487-51-bsa-and-azide-free-detector-ab259686--sandwich-elisa-img52749.jpg)
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일반 정보
기능
May be involved in cell adhesion and cell matrix association. May play a role in the regulation of anchorage versus migration or proliferation versus differentiation via its phosphorylation. May be a novel marker for leukemia diagnosis and for immature hematopoietic stem cell subsets. Belongs to the tetraspanin web involved in tumor progression and metastasis.
Post-translational modifications
Phosphorylated on tyrosine by kinases of the SRC family such as SRC and YES as well as by the protein kinase C gamma/PRKCG. Dephosphorylated by phosphotyrosine phosphatases. Also phosphorylated by suramin, a heparin analog. Tyrosine phosphorylated in response to dissociation of integrin alpha-6 beta-4 from laminin-5 (By similarity).. N-glycosylated.. A soluble form may also be produced by proteolytic cleavage at the cell surface (shedding). Another peptide of 80 kDa (p80) is present in cultured keratinocytes probably due to tryptic cleavage at an unidentified site on the N-terminal side. Converted to p80 by plasmin, a trypsin-like protease (By similarity).
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