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AB276805

Recombinant Mouse Hemopexin protein (His tag)

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Recombinant Mouse Hemopexin protein (His tag) is a Mouse Full Length protein, in the 1 to 460 aa range, expressed in HEK 293 cells, with >98%, < 1 EU/µg endotoxin level, suitable for SDS-PAGE.

대체 명칭 보기

Hpxn, Hpx, Hemopexin

1 이미지
SDS-PAGE - Recombinant Mouse Hemopexin protein (His tag) (AB276805)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Mouse Hemopexin protein (His tag) (AB276805)

SDS-PAGE analysis of ab276805

주요 정보

Purity

>98% SDS-PAGE

Endotoxin 레벨

< 1 EU/µg

발현 시스템

HEK 293 cells

Tags

His tag C-Terminus

Applications

SDS-PAGE

applications

Biologically active

No

Accession

Animal free

No

Carrier free

No

Species

Mouse

보관 버퍼

pH: 6 Constituents: 0.87% Sodium chloride, 0.39% MES

storage-buffer

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보완 제품

Proteins & Peptides

AB316410

Recombinant Human AGT Protein Standard (His tag)

Sandwich ELISA - Recombinant Human AGT Protein Standard (His tag) (AB316410)

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AB123158

Recombinant Human Glutathione Peroxidase 3/GPx-3 protein (His tag N-Terminus)

SDS-PAGE - Recombinant Human Glutathione Peroxidase 3/GPx-3 protein (His tag N-Terminus) (AB123158)

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Proteins & Peptides

AB113594

Recombinant Human FAT10 protein (His tag N-Terminus)

SDS-PAGE - Recombinant Human FAT10 protein (His tag N-Terminus) (AB113594)

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Proteins & Peptides

AB322095

Recombinant Mouse Haptoglobin Protein Standard (His tag)

Sandwich ELISA - Recombinant Mouse Haptoglobin Protein Standard (His tag) (AB322095)

  • 0
  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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서열 정보

[{"linker":null,"sequence":"MARTAVALNILVLLGLCWSLAVASPLPTANGRVAEVENGTKPDSDVPEHCLDTWSFDAATMDHNGTMLFFKGEFVWRGHSGTRELISARWKNPITSVDAAFRGPDSVFLIKEDKVWVYPPEKKENGYPKLFQEEFPGIPYPPDAAVECHRGECQSEGVLFFQGNRKWFWDFATRTQKERSWSTVGNCTAALRWLERYYCFQGNKFLRFNPVTGEVPPRYPLDARDYFVSCPGRGHGRPRNGTAHGNSTHPMHSRCSPDPGLTALLSDHRGATYAFTGSHYWRLDSSRDGWHSWPIAHHWPQGPSTVDAAFSWDDKVYLIQGTQVYVFLTKGGNNLVSGYPKRLEKELGSPPGISLETIDAAFSCPGSSRLYVSSGRRLWWLDLKSGAQATWTEVSWPHEKVDGALCLDKSLGPNTCSSNGSSLYFIHGPNLYCYSSIDKLNAAKSLPQPQKVNSILGCSQ","proteinLength":"Full Length","predictedMolecularWeight":"50.4 kDa","actualMolecularWeight":null,"aminoAcidEnd":460,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"HEK 293 cells","accessionNumber":"Q91X72","tags":[{"tag":"His","terminus":"C-Terminus"}]}]
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특성 및 보관 정보

제형
Lyophilized
배송 시 보관 조건
Ambient - Can Ship with Ice
적절한 단기 보관 조건
-20°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
False
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

Hemopexin also known as HPX is a glycoprotein that transports heme in the blood. It has a molecular weight of approximately 57 kDa and is primarily expressed in the liver. Hemopexin binds to free heme with high affinity which prevents oxidative damage and conserves iron. It transports the heme to hepatocytes for breakdown and recycling protecting cells from iron-mediated toxicity and oxidative stress.
Biological function summary

The hemopexin function relates to protecting tissues from the harmful effects of free heme. Hemopexin does not work as part of a complex in this process but mainly acts independently. Its high binding affinity plays an important role in maintaining heme homeostasis in the plasma and tissues. By controlling heme levels hemopexin supports overall cellular health and function.

Pathways

The hemopexin molecular weight allows it to fit effectively within the heme metabolism and iron recycling pathways. This protein plays a significant role by delivering heme to the liver and facilitating its degradation by heme oxygenase. Hemopexin interacts closely with heme oxygenase and albumin two proteins important for the management of heme and iron levels in the body.

Several hemopexin functions contribute to the understanding of conditions such as hemolytic anemia and acute liver injury. In hemolytic anemia hemopexin helps mitigate the effects of increased heme levels due to excessive red blood cell breakdown. In the context of liver injury the protein assists in the detoxification process and supports hepatic function. Hemopexin-related proteins such as heme oxygenase link these diseases to hemopexin by their roles in managing oxidative stress and heme catabolism.
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일반 정보

기능

Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.

서열 유사성

Belongs to the hemopexin family.

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제품 프로토콜

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타겟 정보

Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.
See full target information Hpx
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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