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AB256040

Recombinant mouse IL-16 protein (Active)

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(1 출판물)

Recombinant mouse IL-16 protein (Active) is a Mouse Fragment protein, in the 1197 to 1322 aa range, expressed in Escherichia coli, with >95%, < 1 EU/µg endotoxin level, suitable for SDS-PAGE, FuncS.

대체 명칭 보기

Pro-interleukin-16, Il16

1 이미지
SDS-PAGE - Recombinant mouse IL-16 protein (Active) (AB256040)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant mouse IL-16 protein (Active) (AB256040)

SDS-PAGE analysis of ab256040 (1μg) under reducing (Lane 1) and non-reducing (Lane 2) conditions. ab256040 is predicted to have a MW of 13.2 kDa

4-20% Tris-Glycine gel. Coomassie Blue staining.

주요 정보

Purity

>95% SDS-PAGE

Endotoxin 레벨

< 1 EU/µg

발현 시스템

Escherichia coli

Tags

Tag free

Applications

SDS-PAGE, FuncS

applications

Biologically active

Yes

Biological activity

Primary human T cell chemotaxis (first detectable at 5 ng/mL).

Accession

Animal free

No

Carrier free

Yes

Species

Mouse

Reconstitution

Reconstitute at 0.1 mg/mL in water

보관 버퍼

Constituents: 0.16% Sodium phosphate

storage-buffer

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보완 제품

Reagents, Controls & Accessories

AB325994

Prestained Protein Ladder - Mid-range molecular weight (11-180 kDa, 4-color)

SDS-PAGE - Prestained Protein Ladder - Mid-range molecular weight (11-180 kDa, 4-color) (AB325994)

  • 0
  • 0
Assay Kits

AB278127

Human Interferon beta ELISA Kit

Recombinant|SimpleStep

ELISA - Human Interferon beta ELISA Kit (AB278127)

  • 0
  • 0
Assay Kits

AB178013

Human IL-6 ELISA Kit

KO Validated|Recombinant|SimpleStep

Sandwich ELISA - Human IL-6 ELISA Kit (AB178013)

  • 5
  • 2
Primary Antibodies

AB207181

Anti-IL-16 antibody [EPR19988]

RabMAb|Recombinant|20ul selling size

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-IL-16 antibody [EPR19988] (AB207181)

  • 0
  • 0
Assay Kits

AB181421

Human TNF alpha ELISA Kit

KO Validated|Recombinant|SimpleStep

Sandwich ELISA - Human TNF alpha ELISA Kit (AB181421)

  • 5
  • 4
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "FuncS": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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서열 정보

[{"linker":null,"sequence":"MHDLNSSTDSAASASAASDISVESKEATVCTVTLEKTSAGLGFSLEGGKGSLHGDKPLTINRIFKGDRTGEMVQPGDEILQLAGTAVQGLTRFEAWNVIKALPDGPVTIVIRRTSLQCKQTTASADS","proteinLength":"Fragment","predictedMolecularWeight":"13.2 kDa","actualMolecularWeight":null,"aminoAcidEnd":1322,"aminoAcidStart":1197,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"O54824","tags":[]}]
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특성 및 보관 정보

제형
Lyophilized
배송 시 보관 조건
Ambient - Can Ship with Ice
적절한 단기 보관 조건
-20°C
적절한 장기 보관 조건
-20°C
True
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일반 정보

기능

Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4.. Isoform 1 may act as a scaffolding protein that anchors ion channels in the membrane.. Isoform 2 is involved in cell cycle progression in T-cells. Appears to be involved in transcriptional regulation of SKP2 and is probably part of a transcriptional repression complex on the core promoter of the SKP2 gene. May act as a scaffold for GABPB1 (the DNA-binding subunit the GABP transcription factor complex) and HDAC3 thus maintaining transcriptional repression and blocking cell cycle progression in resting T-cells.

Post-translational modifications

Synthesized as a chemo-attractant inactive precursor which is proteolytically cleaved by caspase-3 to yield IL-16.

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제품 프로토콜

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타겟 정보

Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4.. Isoform 1 may act as a scaffolding protein that anchors ion channels in the membrane.. Isoform 2 is involved in cell cycle progression in T-cells. Appears to be involved in transcriptional regulation of SKP2 and is probably part of a transcriptional repression complex on the core promoter of the SKP2 gene. May act as a scaffold for GABPB1 (the DNA-binding subunit the GABP transcription factor complex) and HDAC3 thus maintaining transcriptional repression and blocking cell cycle progression in resting T-cells.
See full target information Il16
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제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Emerging microbes & infections 13:2322663 PubMed38380651

2024

hijacks host macrophages-derived interleukin 16 to block phagolysosome maturation for enhancing intracellular growth.

Applications

Unspecified application

Species

Unspecified reactive species

Haibo Su,Shufeng Weng,Liulin Luo,Qin Sun,Taiyue Lin,Huixia Ma,Yumo He,Jing Wu,Honghai Wang,Wenhong Zhang,Ying Xu
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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