Recombinant Mouse MSTN Protein is a Mouse Full Length protein, in the 25 to 376 aa range, expressed in HEK 293 cells, with >95%, <0.005 EU/µg endotoxin level.
대체 명칭 보기
Gdf8, Mstn, Growth/differentiation factor 8, GDF-8, Myostatin
- Mass Spec
Supplier Data
Mass Spectrometry - Recombinant Mouse MSTN Protein (AB283413)
Mass determination by ESI-TOF. Predicted MW is 40143.85 Da (+/- 10 Da by ESI-TOF). Observed MW is 40145.89 Da.
- HPLC
Supplier Data
HPLC - Recombinant Mouse MSTN Protein (AB283413)
HPLC analysis of ab283413
- SDS-PAGE
Supplier Data
SDS-PAGE - Recombinant Mouse MSTN Protein (AB283413)
SDS-PAGE of ab283413
보완 제품
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GDF8 / Myostatin antibody [6E4B2] (AB201954)](https://content.abcam.com/products/images/gdf8-myostatin-antibody-6e4b2-ab201954--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img134531.jpg)
서열 정보
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일반 정보
기능
Acts specifically as a negative regulator of skeletal muscle growth.
서열 유사성
Belongs to the TGF-beta family.
Post-translational modifications
Synthesized as large precursor molecule that undergoes proteolytic cleavage to generate an N-terminal propeptide and a disulfide linked C-terminal dimer, which is the biologically active molecule. The circulating form consists of a latent complex of the C-terminal dimer and other proteins, including its propeptide, which maintain the C-terminal dimer in a latent, inactive state. Ligand activation requires additional cleavage of the prodomain by a tolloid-like metalloproteinase (PubMed:14671324).
타겟 정보
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