Recombinant Mouse SAA1 protein (Tagged) is a Mouse Full Length protein, in the 20 to 122 aa range, expressed in Escherichia coli, with >90%, suitable for SDS-PAGE.
대체 명칭 보기
Serum amyloid A-1 protein, Saa1
- SDS-PAGE
Supplier Data
SDS-PAGE - Recombinant Mouse SAA1 protein (Tagged) (AB235967)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) analysis with 5% enrichment gel and 15% separation gel of ab235967.
보완 제품
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서열 정보
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보관 정보
추가 정보
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
This protein regulates cholesterol metabolism and serves as a chemoattractant directing cell movement towards the sites of inflammation. SAA1 does not exist alone often associating with high-density lipoproteins (HDL) in circulation. By binding to HDL it can aid in transporting cholesterol from tissues to the liver for excretion linking it with both immunological and metabolic processes.
Pathways
Researchers place SAA1 within the inflammation and immune response strategies. It significantly contributes to the acute-phase response and relates to cytokine signaling pathways. SAA1 interacts with proteins such as interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-alpha) which are central to the activation and propagation of inflammatory responses in tissues.
일반 정보
기능
Major acute phase protein.
서열 유사성
Belongs to the SAA family.
Product promise
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