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AB219288

Recombinant Rat IL-11RA protein (His tag C-Terminus)

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Recombinant Rat IL-11RA protein (His tag C-Terminus) is a Rat Fragment protein, in the 24 to 371 aa range, expressed in Baculovirus infected insect cells, with >85%, < 1 EU/µg endotoxin level, suitable for SDS-PAGE.

대체 명칭 보기

Interleukin-11 receptor subunit alpha, IL-11 receptor subunit alpha, IL-11R subunit alpha, IL-11R-alpha, IL-11RA, Il11ra1

1 이미지
SDS-PAGE - Recombinant Rat IL-11RA protein (His tag C-Terminus) (AB219288)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Rat IL-11RA protein (His tag C-Terminus) (AB219288)

15% SDS-PAGE analysis of 3 μg ab219288.

주요 정보

Purity

>85% SDS-PAGE

Affinity purified

Endotoxin 레벨

< 1 EU/µg

발현 시스템

Baculovirus infected insect cells

Tags

His tag C-Terminus

Applications

SDS-PAGE

applications

Biologically active

No

Accession

Animal free

No

Carrier free

No

Species

Rat

보관 버퍼

pH: 7.4 Constituents: PBS, 10% Glycerol (glycerin, glycerine)

storage-buffer

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보완 제품

Primary Antibodies

AB125015

Anti-IL-11RA antibody [EPR5446]

RabMAb|Recombinant

Immunocytochemistry/ Immunofluorescence - Anti-IL-11RA antibody [EPR5446] (AB125015)

  • 0
  • 0
Primary Antibodies

AB187167

Anti-IL-11 antibody [EPR15253]

RabMAb|Recombinant

Western blot - Anti-IL-11 antibody [EPR15253] (AB187167)

  • 0
  • 0
Proteins & Peptides

AB281801

Recombinant human IL-11 protein (Active)

Premium Bioactive

Mass Spectrometry - Recombinant human IL-11 protein (Active) (AB281801)

  • 0
  • 0
Secondary Antibodies

AB125912

Rabbit monoclonal [H26-10] Anti-Human IgG1 H&L

RabMAb|Recombinant

ELISA - Rabbit monoclonal [H26-10] Anti-Human IgG1 H&L (AB125912)

  • 0
  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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서열 정보

[{"sequence":"TPCPQAWGPPGVQYGQPGRPVMLCCPGVNAGTPVSWFRDGDSRLLQGPDSGLGHRLVLAQVDSRDEGTYVCRTLDGVFGGMVTLKLGSPPARPEVSCQAVDYENFSCTWSPGRVSGLPTRYLTSYRKKTLPGAESQRESPSTGPWPCPQDPLEASRCVVHGAEFWSEYRINVTEVNPLGASTCLLDVRLQRILRPDPPQGLRVESVPGYPRRLHASWTYPASWRRQPHFLLKFRLQYRPAQHPAWSTVEPIGLEELITDAVAGLPHAVRVSARDFLDAGTWSAWSPEAWGTPSTGPLRDEVPDGSRGHEQKLEAAAQEDSPAPPSPSLQPDPRPLDHRDPLEQVAVLAVEHHHHHH","proteinLength":"Fragment","predictedMolecularWeight":"39.2 kDa","actualMolecularWeight":null,"aminoAcidEnd":371,"aminoAcidStart":24,"nature":"Recombinant","expressionSystem":"Baculovirus infected insect cells","accessionNumber":"Q99MF4","tags":[{"tag":"His","terminus":"C-Terminus"}]}]
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특성 및 보관 정보

제형
Liquid
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
False
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일반 정보

기능

Receptor for interleukin-11 (IL11). The receptor systems for IL6, LIF, OSM, CNTF, IL11 and CT1 can utilize IL6ST for initiating signal transmission. The IL11/IL11RA/IL6ST complex may be involved in the control of proliferation and/or differentiation of skeletogenic progenitor or other mesenchymal cells. Essential for the normal development of craniofacial bones and teeth. Restricts suture fusion and tooth number.. Soluble interleukin-11 receptor subunit alpha. Soluble form of IL11 receptor (sIL11RA) that acts as an agonist of IL11 activity. The IL11 : sIL11RA complex binds to IL6ST/gp130 on cell surfaces and induces signaling also on cells that do not express membrane-bound IL11RA in a process called IL11 trans-signaling.

서열 유사성

Belongs to the type I cytokine receptor family. Type 3 subfamily.

Post-translational modifications

A short soluble form is also released from the membrane by proteolysis. The sIL11RA is formed either by limited proteolysis of membrane-bound receptors, a process referred to as ectodomain shedding, or directly secreted from the cells after alternative mRNA splicing. mIL11RA is cleaved by the proteases ADAM10, ELANE and PRTN3.

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제품 프로토콜

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타겟 정보

Receptor for interleukin-11 (IL11). The receptor systems for IL6, LIF, OSM, CNTF, IL11 and CT1 can utilize IL6ST for initiating signal transmission. The IL11/IL11RA/IL6ST complex may be involved in the control of proliferation and/or differentiation of skeletogenic progenitor or other mesenchymal cells. Essential for the normal development of craniofacial bones and teeth. Restricts suture fusion and tooth number.. Soluble interleukin-11 receptor subunit alpha. Soluble form of IL11 receptor (sIL11RA) that acts as an agonist of IL11 activity. The IL11 : sIL11RA complex binds to IL6ST/gp130 on cell surfaces and induces signaling also on cells that do not express membrane-bound IL11RA in a process called IL11 trans-signaling.
See full target information Il11ra1
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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