Recombinant Salmonella typhi OmpA protein (His tag)

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Biological function summary

OmpA plays a critical role in interactions between the bacterial cell and its environment. It is involved in cell adhesion and invasion influencing the bacterium's ability to establish infection. This protein does not typically exist as part of a larger complex yet it contributes to the structural and functional roles of the bacterial outer membrane. Furthermore it aids in the stabilization of the outer membrane by interacting with other components including lipopolysaccharides.

Pathways

OmpA is integral to bacterial nutrient uptake mechanisms and the response to environmental changes. It participates in the pathway for porin-mediated transport which includes proteins like FepA another outer membrane protein involved in iron transport. Through its channel-forming properties OmpA influences the diffusion of small molecules and ions underlining its involvement in vital processes of cellular homeostasis and response to oxidative stress.