Recombinant Saxiphilin protein (His tag)

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This supplementary information is collated from multiple sources and compiled automatically.

Biological function summary

Saxiphilin acts as a detoxifying agent against neurotoxins by binding to them and sequestering them away from sensitive neurological targets. Unlike many detoxification processes that involve multi-protein complexes saxiphilin operates independently. Its structural relationship with transferrin suggests it might have a role in iron or other metal ion transport or modulation although the primary focus remains on its toxin-binding activities.

Pathways

Saxiphilin is involved in processes that affect the neurological system's response to toxins. It participates in the regulation of sodium channel blockers by sequestering saxitoxin. While not part of a signaling cascade its activity influences proteins like the voltage-gated sodium channels by preventing toxin binding which is important for maintaining proper nerve function.