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AB237746

Recombinant UVSX protein (Tagged)

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Recombinant UVSX protein (Tagged) is a Enterobacteria phage T4 Full Length protein, in the 1 to 391 aa range, expressed in Escherichia coli, with >90%, suitable for SDS-PAGE, Mass Spec.

대체 명칭 보기

Recombination and repair protein, UVSX

3 이미지
Mass Spectrometry - Recombinant UVSX protein (Tagged) (AB237746)
  • Mass Spec

Supplier Data

Mass Spectrometry - Recombinant UVSX protein (Tagged) (AB237746)

Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of ab237746 could indicate that this peptide derived from E.coli-expressed Enterobacteria phage T4 (Bacteriophage T4)UVSX.

Mass Spectrometry - Recombinant UVSX protein (Tagged) (AB237746)
  • Mass Spec

Supplier Data

Mass Spectrometry - Recombinant UVSX protein (Tagged) (AB237746)

Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of ab237746 could indicate that this peptide derived from E.coli-expressed Enterobacteria phage T4 (Bacteriophage T4) UVSX.

SDS-PAGE - Recombinant UVSX protein (Tagged) (AB237746)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant UVSX protein (Tagged) (AB237746)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) analysis with 5% enrichment gel and 15% separation gel of ab237746.

주요 정보

Purity

>90% SDS-PAGE

발현 시스템

Escherichia coli

Tags

6x His tag N-Terminus SUMO tag N-Terminus

Applications

SDS-PAGE, Mass Spec

applications

Biologically active

No

Accession

Animal free

No

Carrier free

No

Species

Enterobacteria phage T4

보관 버퍼

pH: 7.2 - 7.4 Constituents: Tris buffer, 50% Glycerol (glycerin, glycerine)

storage-buffer

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보완 제품

Proteins & Peptides

AB225610

Recombinant uvsY protein (His tag)

Mass Spectrometry - Recombinant uvsY protein (His tag) (AB225610)

  • 0
  • 0
Primary Antibodies

AB219465

Anti-6X His tag® antibody [RMH01]

Recombinant|Lab Essentials

Sandwich ELISA - Anti-6X His tag® antibody [RMH01] (AB219465)

  • 0
  • 0
Assay Kits

AB253778

Human GAPDH Antibody Pair - BSA and Azide free

RabMAb|Recombinant

Sandwich ELISA - Human GAPDH Antibody Pair - BSA and Azide free (AB253778)

  • 0
  • 0
Primary Antibodies

AB9225

Anti-M13 Bacteriophage Coat Protein g8p antibody [RL-ph2]

Western blot - Anti-M13 Bacteriophage Coat Protein g8p antibody [RL-ph2] (AB9225)

  • 4
  • 3
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "Mass Spec": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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서열 정보

[{"linker":null,"sequence":"MSDLKSRLIKASTSKLTAELTASKFFNEKDVVRTKIPMMNIALSGEITGGMQSGLLILAGPSKSFKSNFGLTMVSSYMRQYPDAVCLFYDSEFGITPAYLRSMGVDPERVIHTPVQSLEQLRIDMVNQLDAIERGEKVVVFIDSLGNLASKKETEDALNEKVVSDMTRAKTMKSLFRIVTPYFSTKNIPCIAINHTYETQEMFSKTVMGGGTGPMYSADTVFIIGKRQIKDGSDLQGYQFVLNVEKSRTVKEKSKFFIDVKFDGGIDPYSGLLDMALELGFVVKPKNGWYAREFLDEETGEMIREEKSWRAKDTNCTTFWGPLFKHQPFRDAIKRAYQLGAIDSNEIVEAEVDELINSKVEKFKSPESKSKSAADLETDLEQLSDMEEFNE","proteinLength":"Full Length","predictedMolecularWeight":"60 kDa","actualMolecularWeight":null,"aminoAcidEnd":391,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"P04529","tags":[{"tag":"6x His","terminus":"N-Terminus"},{"tag":"SUMO","terminus":"N-Terminus"}]}]
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특성 및 보관 정보

제형
Liquid
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
-20°C
적절한 장기 보관 조건
-20°C
보관 정보
Avoid freeze / thaw cycle
False
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

UVSX also known as Ubiquitin Variant X is a protein involved in protein ubiquitination. It has a molecular mass of approximately 37 kDa. UVSX is primarily expressed in the liver and kidney where it regulates various cellular processes. As a ubiquitin-like protein it binds to substrates tagging them for degradation via the proteasome pathway—a critical mechanism for maintaining protein homeostasis within cells.
Biological function summary

UVSX functions as an important component in biochemical pathways involved in protein turnover and stress responses. It is not part of a larger protein complex but operates independently to facilitate the breakdown of misfolded or damaged proteins. By modulating the ubiquitin-proteasome system UVSX ensures that cells eliminate excess proteins which is important for cell health and function.

Pathways

UVSX integrates into the proteasome pathway specifically influencing protein degradation processes. It closely interacts with the E3 ubiquitin ligase another pivotal protein in this system to select specific substrates for degradation. Additionally UVSX has a role in the cell cycle regulation pathway impacting cellular proliferation and division.

UVSX contributes to the pathogenesis of cancers and neurodegenerative diseases. For example its dysfunction or overexpression can lead to uncontrolled cell growth in certain types of cancer. The protein also links to Alzheimer's disease with aberrant UVSX activity affecting the accumulation of damaged proteins in neurons potentially worsening disease progression. UVSX's interaction with protein targets like p53—a tumor suppressor protein—illustrates its involvement in both these conditions.
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일반 정보

기능

Important in genetic recombination, DNA repair, and replication. Possesses pairing and strand-transfer activity. Interacts with dda and gene 32 proteins.

서열 유사성

Belongs to the RecA family.

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제품 프로토콜

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타겟 정보

Important in genetic recombination, DNA repair, and replication. Possesses pairing and strand-transfer activity. Interacts with dda and gene 32 proteins.
See full target information UVSX
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Product promise

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