Carboxyl Gold Nanoparticles (40nm, 40OD)

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Carboxyl Gold Nanoparticles (40nm, 40OD) (ab269942) are coated gold nanoparticles functionalized with carboxyl groups that allow the covalent conjugation of antibodies, using the water-soluble carbodiimide crosslinker EDC.

Unlike traditional EDC/NHS coupling used to activate carboxyl groups, Carboxyl Gold Nanoparticles (40nm, 40OD) (ab269942) are optimized for single step EDC covalent coupling without signs of aggregation. This eliminates the need for EDC/NHS pre-activation and washing steps associated with traditional conjugations.

This process is also significantly faster than standard methods, with conjugates ready to use in less than 35 minutes.

Carboxyl Gold Nanoparticles (40nm, 40OD) (ab269942) have a narrow size distribution, a uniform spherical shape and high batch-to-batch consistency:

Mean Diameter 36-44 nm
SD <4 nm
CV% <10%

Product Details

Composition: 40nm carboxyl-gold 40 OD carboxyl gold nanoparticles
Size: 40 nm
Adsorption max: 530 nm
OD: 40.0
Particles per mL: 36 x 10¹¹
Volume: 1 mL and 5 mL
Buffer: 10 mM EPPS, pH 8.5

Benefits of Carboxyl Gold Nanoparticles (40nm, 40 OD):

Easy protocol - conjugate ready to use in less than 35 min, with no additional pre-activation or wash steps

Proprietary surface coating prevents metal-protein interactions, and enables covalent attachment to the gold-stable conjugates formed

Uniform spherical shape and narrow size distribution - consistent high quality and batch to batch reproducibility

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Check out our Gold Conjugation range here

This product is manufactured by Expedeon, an Abcam company. It was previously called 40nm InnovaCoat® GOLD - Carboxyl (40 OD). Expedeon productcode 3400-0001 is the same as the 40 µg size of this product and code 3400-0005 is the same as the 200 µg size of this product.