G
Function
Attaches the virus to host LDL receptors, inducing clathrin-dependent endocytosis of the virion (By similarity). In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and endosomal membrane (PubMed:20921141).
Post-translational modifications
Glycosylated by host. Palmitoylated by host.
Sequence Similarities
Belongs to the vesiculovirus glycoprotein family.
Cellular localization
- Virion membrane
- Single-pass type I membrane protein
- Host membrane
- Single-pass type I membrane protein
Alternative names
Glycoprotein, G