Overview

  • Product name

    Anti-KRT72 antibody
  • Description

    Rabbit polyclonal to KRT72
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 217-434 of Human KRT72 (UniProt Q14CN4).

  • Positive control

    • NT2D1 whole cell lysate; Human colon carcinoma tissue
  • General notes

    Store undiluted.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.00
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab127030 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 56 kDa.
IHC-P 1/100 - 1/500. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

Target

  • Function

    Has a role in hair formation. Specific component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle.
  • Tissue specificity

    Highly expressed in hair follicles from scalp and eyebrow. Also expressed in palmoplantar epidermis. Not expressed in face skin despite the presence of fine hairs histologically. In hair, it is specifically present in the inner root sheath (IRS) of the hair follicle. Present in the IRS cuticle, but not in Henle or Huxley layers of the IRS. In the IRS cuticle, its presence is delayed up to the height of the apex of the dermal papilla (at protein level).
  • Sequence similarities

    Belongs to the intermediate filament family.
  • Information by UniProt
  • Database links

  • Alternative names

    • K6IRS2 antibody
    • CK-72 antibody
    • Cytokeratin-72 antibody
    • K2C72_HUMAN antibody
    • K6irs antibody
    • K72 antibody
    • KB35 antibody
    • Keratin 6 inner root sheath 2 antibody
    • Keratin antibody
    • keratin protein K6irs antibody
    • Keratin type II cytoskeletal 72 antibody
    • Keratin-72 antibody
    • KRT6 antibody
    • KRT6IRS2 antibody
    • Krt72 antibody
    • type II cytoskeletal 72 antibody
    • Type II inner root sheath-specific keratin-K6irs2 antibody
    • Type-II keratin Kb35 antibody
    see all

Images

  • Anti-KRT72 antibody (ab127030) at 1/1000 dilution + NT2D1 whole cell
    lysate at 30 µg

    Predicted band size: 56 kDa



    10% SDS-PAGE
  • ab127030, at 1/500 dilution, staining KRT72 in paraffin-embedded Human colon carcinoma tissue by Immunohistochemistry.

References

ab127030 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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