Overview

  • Product name

    Anti-KRT81 antibody - N-terminal
    See all KRT81 primary antibodies
  • Description

    Rabbit polyclonal to KRT81 - N-terminal
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Fusion protein corresponding to Human KRT81 (N terminal). (BC117465).
    Database link: Q14533

  • Positive control

    • HeLa whole cell lysate (ab150035); Human cervical cancer tissue.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.3
    Preservative: 0.05% Sodium azide
    Constituents: 49% PBS, 50% Glycerol
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab197356 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/200 - 1/1000. Predicted molecular weight: 55 kDa.
IHC-P 1/15 - 1/50.

Target

  • Tissue specificity

    Abundantly expressed in the differentiating cortex of growing (anagen) hair. Expression is restricted to the keratinocytes of the hair cortex and is absent from inner root sheath and medulla. Expressed in malignant lymph node tissue in breast carcinoma tissue.
  • Involvement in disease

    Defects in KRT81 are a cause of monilethrix (MLTRX) [MIM:158000]. Monilethrix is an autosomal dominant hair disorder characterized clinically by alopecia and follicular papules. Affected hairs have uniform elliptical nodes of normal thickness and intermittent constrictions, internodes at which the hair easily breaks. Usually only the scalp is involved, but in severe forms, the secondary sexual hair, eyebrows, eyelashes, and nails may also be affected.
  • Sequence similarities

    Belongs to the intermediate filament family.
  • Information by UniProt
  • Database links

  • Alternative names

    • 1 antibody
    • basic antibody
    • ghHb 1 antibody
    • ghHb1 antibody
    • ghHkb 1 antibody
    • ghHKb1 antibody
    • hair antibody
    • Hair keratin K2.9 antibody
    • Hard keratin type II 1 antibody
    • HB 1 antibody
    • HB1 antibody
    • hHAKB2 1 antibody
    • K2.9 antibody
    • K81 antibody
    • Keratin 81 antibody
    • Keratin antibody
    • Keratin hair basic 1 antibody
    • Keratin type II cuticular Hb1 antibody
    • Keratin-81 antibody
    • Keratin81 antibody
    • KRT 81 antibody
    • KRT81 antibody
    • KRT81_HUMAN antibody
    • KRTHB 1 antibody
    • KRTHB1 antibody
    • Metastatic lymph node 137 gene protein antibody
    • MLN 137 antibody
    • MLN137 antibody
    • type II cuticular Hb1 antibody
    • Type II hair keratin Hb1 antibody
    • Type-II keratin Kb21 antibody
    see all

Images

  • Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue labeling KRT81 with ab197356 at 1/15 dilution.

  • Anti-KRT81 antibody - N-terminal (ab197356) at 1/200 dilution + HeLa cell lysate at 40 µg

    Predicted band size: 55 kDa



    Gel: 10%SDS-PAGE.

    Exposure time: 30 seconds

References

ab197356 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab197356.
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