Overview

  • Product name
    Anti-Kv beta 1 antibody - N-terminal
    See all Kv beta 1 primary antibodies
  • Description
    Rabbit polyclonal to Kv beta 1 - N-terminal
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human Kv beta 1 aa 14-44 (N terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Database link: Q14722

  • Positive control
    • MDA-MB453 cell lysate.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    ab174508 was purified through a protein A column, followed by peptide affinity purification.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab174508 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 47 kDa.

Target

  • Function
    Accessory potassium channel protein which modulates the activity of the pore-forming alpha subunit. All three isoforms alter the functional properties of Kv1.4 and Kv1.5. Isoform KvB1.2 has no effect on Kv1.1, Kv1.2 or Kv2.1.
  • Tissue specificity
    In brain, expression is most prominent in caudate nucleus, hippocampus and thalamus. Significant expression also detected in amygdala and subthalamic nucleus. Also expressed in both healthy and cardiomyopathic heart. Up to four times more abundant in left ventricle than left atrium.
  • Sequence similarities
    Belongs to the shaker potassium channel beta subunit family.
  • Domain
    Alteration of functional properties of alpha subunit is mediated through N-terminal domain of beta subunit.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • hKvb3 antibody
    • hKvBeta3 antibody
    • K(+) channel subunit beta-1 antibody
    • KCAB1_HUMAN antibody
    • KCNA1B antibody
    • KCNAB1 antibody
    • Kv-beta-1 antibody
    • Kvb1.3 antibody
    • Voltage-gated potassium channel beta-1 subunit antibody
    • Voltage-gated potassium channel subunit beta-1 antibody
    see all

Images

  • Anti-Kv beta 1 antibody - N-terminal (ab174508) at 1/100 dilution + MDA-MB453 cell lysate at 35 µg

    Predicted band size: 47 kDa

References

ab174508 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab174508.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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