Overview

  • Product name

  • Description

    Rabbit polyclonal to Kv1.4/RK3
  • Host species

    Rabbit
  • Specificity

    No cross reactivity with other proteins.
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Rat, Human
    Predicted to work with: Mouse, Cow
  • Immunogen

    Synthetic peptide corresponding to Human Kv1.4/RK3 aa 329-344 (internal sequence).
    Sequence:

    LPEFRDDRDLVMALSA


    Database link: P22459

  • Positive control

    • Rat brain tissue lysate; HY1080, PANC, U87 and SHG cell lysates
  • General notes

     This product was previously labelled as Kv1.4

     

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    Preservatives: 0.025% Thimerosal (merthiolate), 0.025% Sodium azide
    Constituents: 2.5% BSA, 0.45% Sodium chloride, 0.1% Dibasic monohydrogen sodium phosphate
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab191052 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.1 - 0.5 µg/ml. Predicted molecular weight: 73 kDa.

Target

  • Function

    Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.
  • Sequence similarities

    Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.4/KCNA4 sub-subfamily.
  • Domain

    The N-terminus may be important in determining the rate of inactivation of the channel while the tail may play a role in modulation of channel activity and/or targeting of the channel to specific subcellular compartments.
    The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • Voltage gated K+ channel HuKII antibody
    • Fetal skeletal muscle potassium channel antibody
    • HBK4 antibody
    • HK1 antibody
    • HPCN2 antibody
    • HUKII antibody
    • Kcna4 antibody
    • KCNA4_HUMAN antibody
    • KCNA4L antibody
    • KCNA8 antibody
    • kv1.4 antibody
    • PCN2 antibody
    • Potassium channel 2 antibody
    • Potassium voltage gated channel shaker related subfamily member 4 antibody
    • Potassium voltage gated channel subfamily A member 4 antibody
    • Potassium voltage-gated channel subfamily A member 4 antibody
    • Rapidly inactivating potassium channel antibody
    • Shaker related potassium channel Kv1.4 antibody
    • Type A potassium channel antibody
    • Voltage gated potassium channel HBK4 antibody
    • Voltage gated potassium channel HK1 antibody
    • Voltage gated potassium channel subunit Kv1.4 antibody
    • Voltage-gated K(+) channel HuKII antibody
    • Voltage-gated potassium channel HBK4 antibody
    • Voltage-gated potassium channel HK1 antibody
    • Voltage-gated potassium channel subunit Kv1.4 antibody
    see all

Images

  • All lanes : Anti-Kv1.4/RK3 antibody (ab191052) at 0.5 µg/ml

    Lane 1 : Rat brain tissue Lysate
    Lane 2 : HY1080 Whole Cell Lysate
    Lane 3 : PANC Whole Cell Lysate
    Lane 4 : U87 Whole Cell Lysate
    Lane 5 : SHG Whole Cell Lysate

    Predicted band size: 73 kDa

References

ab191052 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab191052.
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