• Product name
  • Description
    Rabbit polyclonal to Kv4.3
  • Host species
  • Tested applications
    Suitable for: IHC-P, IHC-Fr, WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide derived from the N terminal domain of human Kv4.3.



Our Abpromise guarantee covers the use of ab65794 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use at an assay dependent concentration.
IHC-Fr Use at an assay dependent concentration.
WB 1/200 - 1/2000. Predicted molecular weight: 73 kDa.


  • Function
    Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to I(To) current in heart and I(Sa) current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits.
  • Tissue specificity
    Highly expressed in heart and brain, in particular in cortex, cerebellum, amygdala and caudate nucleus. Detected at lower levels in liver, skeletal muscle, kidney and pancreas. Isoform 1 predominates in most tissues. Isoform 1 and isoform 2 are detected at similar levels in brain, skeletal muscle and pancreas.
  • Sequence similarities
    Belongs to the potassium channel family. D (Shal) (TC 1.A.1.2) subfamily. Kv4.3/KCND3 sub-subfamily.
  • Domain
    The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.
  • Cellular localization
    Membrane. Cell membrane > sarcolemma.
  • Information by UniProt
  • Database links
  • Alternative names
    • KCND 3 antibody
    • KCND 3L antibody
    • KCND 3S antibody
    • Kcnd3 antibody
    • KCND3_HUMAN antibody
    • KCND3L antibody
    • KCND3S antibody
    • KSHIVB antibody
    • Kv 4.3 antibody
    • MGC14203 antibody
    • MGC142037 antibody
    • OTTHUMP00000063948 antibody
    • Potassium ioinic channel Kv4.3 antibody
    • Potassium voltage gated channel Shal related subfamily member 3 antibody
    • Potassium voltage gated channel subfamily D member 3 antibody
    • Potassium voltage-gated channel subfamily D member 3 antibody
    • Sha1 related potassium channel Kv4.3 antibody
    • Voltage gated K+ channel antibody
    • Voltage gated potassium channel Kv4.3 antibody
    • Voltage gated potassium channel subunit Kv4.3 antibody
    • Voltage-gated potassium channel subunit Kv4.3 antibody
    see all


This product has been referenced in:
  • Matkovich SJ  et al. MicroRNA-133a protects against myocardial fibrosis and modulates electrical repolarization without affecting hypertrophy in pressure-overloaded adult hearts. Circ Res 106:166-75 (2010). WB ; Human . Read more (PubMed: 19893015) »

See 1 Publication for this product

Customer reviews and Q&As

I understand your concern.

We have not seen any complaints of this type with this antibody. Although I cannot guarantee that your following experiment will not yield similar results, I have seen this type of response with other product befor...

Read More

Thank you for providing this additional information.

It seems apparent that the antibody is reacting to something on this blot. It is usually the case in instances like this that there is reaction to the proteins in your blocking buffer. I w...

Read More

Thank you for providing information.

I am sorry to hear of the issues that you have been experiencing.In order to help with our investigation of this case before deciding how to proceed, I would appreciate if you are able to provide the de...

Read More

Thank you for contacting Abcam. I am sorry to hear that ab65794 has not been working for you. I will be glad to help you find an alternative antibody. To help determine the antibody that will best suit your needs, could you tell me what ...

Read More


Sign up