Overview

  • Product name

    Anti-Kv4.3/KCND3 antibody - C-terminal
    See all Kv4.3/KCND3 primary antibodies
  • Description

    Rabbit polyclonal to Kv4.3/KCND3 - C-terminal
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Chicken, Cow, Rhesus monkey
  • Immunogen

    Recombinant fragment within Human Kv4.3/KCND3 (C terminal). The exact sequence is proprietary.
    Database link: Q9UK17

  • Positive control

    • WB: IMR32 whole cell lysate.
  • General notes

     This product was previously labelled as Kv4.3

     

Properties

Applications

Our Abpromise guarantee covers the use of ab228944 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 73 kDa.

Target

  • Function

    Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to I(To) current in heart and I(Sa) current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits.
  • Tissue specificity

    Highly expressed in heart and brain, in particular in cortex, cerebellum, amygdala and caudate nucleus. Detected at lower levels in liver, skeletal muscle, kidney and pancreas. Isoform 1 predominates in most tissues. Isoform 1 and isoform 2 are detected at similar levels in brain, skeletal muscle and pancreas.
  • Sequence similarities

    Belongs to the potassium channel family. D (Shal) (TC 1.A.1.2) subfamily. Kv4.3/KCND3 sub-subfamily.
  • Domain

    The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.
  • Cellular localization

    Membrane. Cell membrane > sarcolemma.
  • Information by UniProt
  • Database links

  • Alternative names

    • KCND 3 antibody
    • KCND 3L antibody
    • KCND 3S antibody
    • Kcnd3 antibody
    • KCND3_HUMAN antibody
    • KCND3L antibody
    • KCND3S antibody
    • KSHIVB antibody
    • Kv 4.3 antibody
    • MGC14203 antibody
    • MGC142037 antibody
    • OTTHUMP00000063948 antibody
    • Potassium ioinic channel Kv4.3 antibody
    • Potassium voltage gated channel Shal related subfamily member 3 antibody
    • Potassium voltage gated channel subfamily D member 3 antibody
    • Potassium voltage-gated channel subfamily D member 3 antibody
    • Sha1 related potassium channel Kv4.3 antibody
    • Voltage gated K+ channel antibody
    • Voltage gated potassium channel Kv4.3 antibody
    • Voltage gated potassium channel subunit Kv4.3 antibody
    • Voltage-gated potassium channel subunit Kv4.3 antibody
    see all

Images

  • Anti-Kv4.3/KCND3 antibody - C-terminal (ab228944) at 1/1000 dilution + IMR32 (human neuroblast cell line) whole cell lysate at 30 µg

    Developed using the ECL technique.

    Predicted band size: 73 kDa



    7.5% SDS-PAGE gel.

References

ab228944 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab228944.
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