Kynurenic acid, endogenous ionotropic / nicotinic antagonist (ab120064)

Publishing research using ab120064? Please let us know so that we can cite the reference in this datasheet.

ab120064 has been referenced in 26 publications.

  • Heubl M  et al. GABAA receptor dependent synaptic inhibition rapidly tunes KCC2 activity via the Cl--sensitive WNK1 kinase. Nat Commun 8:1776 (2017). PubMed: 29176664
  • Hiu T  et al. Enhanced phasic GABA inhibition during the repair phase of stroke: a novel therapeutic target. Brain 139:468-80 (2016). PubMed: 26685158
  • Zarnowska ED  et al. Etomidate blocks LTP and impairs learning but does not enhance tonic inhibition in mice carrying the N265M point mutation in the beta3 subunit of the GABA(A) receptor. Neuropharmacology 93:171-178 (2015). PubMed: 25680234
  • Shin JH  et al. Muscarinic regulation of dopamine and glutamate transmission in the nucleus accumbens. Proc Natl Acad Sci U S A 112:8124-9 (2015). PubMed: 26080439
  • Maguire EP  et al. Tonic inhibition of accumbal spiny neurons by extrasynaptic a4ßd GABAA receptors modulates the actions of psychostimulants. J Neurosci 34:823-38 (2014). PubMed: 24431441
  • Kupchik YM  et al. Cocaine dysregulates opioid gating of GABA neurotransmission in the ventral pallidum. J Neurosci 34:1057-66 (2014). PubMed: 24431463
  • Grauert A  et al. Endogenous zinc depresses GABAergic transmission via T-type Ca(2+) channels and broadens the time window for integration of glutamatergic inputs in dentate granule cells. J Physiol 592:67-86 (2014). PubMed: 24081159
  • Adrover MF  et al. Glutamate and dopamine transmission from midbrain dopamine neurons share similar release properties but are differentially affected by cocaine. J Neurosci 34:3183-92 (2014). PubMed: 24573277
  • Perin M  et al. Diurnal inhibition of NMDA-EPSCs at rat hippocampal mossy fibre synapses through orexin-2 receptors. J Physiol 592:4277-95 (2014). PubMed: 25085886
  • Félix-Oliveira A  et al. Homeostatic plasticity induced by brief activity deprivation enhances long-term potentiation in the mature rat hippocampus. J Neurophysiol 112:3012-22 (2014). PubMed: 25210161
  • Bock R  et al. Strengthening the accumbal indirect pathway promotes resilience to compulsive cocaine use. Nat Neurosci 16:632-8 (2013). PubMed: 23542690
  • Gunn BG  et al. Dysfunctional astrocytic and synaptic regulation of hypothalamic glutamatergic transmission in a mouse model of early-life adversity: relevance to neurosteroids and programming of the stress response. J Neurosci 33:19534-54 (2013). PubMed: 24336719
  • Christian CA & Huguenard JR Astrocytes potentiate GABAergic transmission in the thalamic reticular nucleus via endozepine signaling. Proc Natl Acad Sci U S A 110:20278-83 (2013). PubMed: 24262146
  • Wu PY  et al. Acid-sensing ion channel-1a is not required for normal hippocampal LTP and spatial memory. J Neurosci 33:1828-32 (2013). PubMed: 23365222
  • Huang L & van Luijtelaar G The effects of responsive and scheduled subicular high frequency stimulation in the intra-hippocampal kainic acid seizure model. Epilepsy Res 106:326-37 (2013). PubMed: 23899954
  • Atanasova M  et al. Strain-dependent effects of long-term treatment with melatonin on kainic acid-induced status epilepticus, oxidative stress and the expression of heat shock proteins. Pharmacol Biochem Behav 111:44-50 (2013). PubMed: 23978502
  • Kaplan JS  et al. Opposite actions of alcohol on tonic GABAA receptor currents mediated by nNOS and PKC activity. Nat Neurosci 16:1783-93 (2013). PubMed: 24162656
  • Pleil KE  et al. Chronic stress alters neuropeptide Y signaling in the bed nucleus of the stria terminalis in DBA/2J but not C57BL/6J mice. Neuropharmacology 62:1777-86 (2012). PubMed: 22182779
  • Klyuch BP  et al. The dynamics of single spike-evoked adenosine release in the cerebellum. J Physiol 589:283-95 (2011). PubMed: 21078589
  • Jin Z  et al. Insulin reduces neuronal excitability by turning on GABA(A) channels that generate tonic current. PLoS One 6:e16188 (2011). PubMed: 21264261
  • Rudolph S  et al. Desynchronization of multivesicular release enhances Purkinje cell output. Neuron 70:991-1004 (2011). PubMed: 21658590
  • Atterbury A & Wall MJ A population of immature cerebellar parallel fibre synapses are insensitive to adenosine but are inhibited by hypoxia. Neuropharmacology 61:880-8 (2011). PubMed: 21693125
  • Gómez-Gonzalo M  et al. Ictal but not interictal epileptic discharges activate astrocyte endfeet and elicit cerebral arteriole responses. Front Cell Neurosci 5:8 (2011). PubMed: 21747758
  • Giesbrecht CJ  et al. Countervailing modulation of Ih by neuropeptide Y and corticotrophin-releasing factor in basolateral amygdala as a possible mechanism for their effects on stress-related behaviors. J Neurosci 30:16970-82 (2010). PubMed: 21159967
  • Losi G  et al. A new experimental model of focal seizures in the entorhinal cortex. Epilepsia 51:1493-502 (2010). PubMed: 20067512
  • Atterbury A & Wall MJ Adenosine signalling at immature parallel fibre-Purkinje cell synapses in rat cerebellum. J Physiol 587:4497-508 (2009). PubMed: 19651764

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