Kynurenic acid sodium salt, Endogenous ionotropic / nicotinic antagonist (ab120256)

Overview

  • Product name
    Kynurenic acid sodium salt, Endogenous ionotropic / nicotinic antagonist
  • Description
    Endogenous ionotropic / nicotinic antagonist; water soluble
  • Biological description
    Endogenous antagonist at ionotropic, glycine and α7 nicotinic receptors. Neuroprotective in vivo. Water soluble form.

    Also available in simple stock solutions (ab146693) - add 1 ml of water to get an exact, ready-to-use concentration.
  • Purity
    > 99%
  • Chemical structure
    Chemical Structure

Properties

References

This product has been referenced in:
  • Grilli M  et al. Modulation of the function of presynaptic alpha7 and non-alpha7 nicotinic receptors by the tryptophan metabolites, 5-hydroxyindole and kynurenate in mouse brain. Br J Pharmacol 149:724-32 (2006). Read more (PubMed: 17016503) »
  • Pittaluga A  et al. The "kynurenate test", a biochemical assay for putative cognition enhancers. J Pharmacol Exp Ther 283:82-90 (1997). Read more (PubMed: 9336311) »
  • Hicks RR  et al. Kynurenate is neuroprotective following experimental brain injury in the rat. Brain Res 655:91-6 (1994). Read more (PubMed: 7812795) »
See all 7 Publications for this product

Customer reviews and Q&As

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Madhura Athreya

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Submitted Apr 01 2016

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