Overview

  • Product name

    L-(+)-Selenomethionine, Antioxidant agent
  • Description

    Antioxidant agent. Glutathione peroxidase inducer.
  • Biological description

    Antioxidant agent. Glutathione peroxidase inducer. Induces apoptosis. Shows antiproliferative effects (IC50 = 45-130 μM). Mitigates the effects of oxidative stress in vivo. Orally active.
  • Purity

    > 99%
  • CAS Number

    3211-76-5
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (2S)-2-Amino-4-(methylseleno)butanoic acid
  • Molecular weight

    196.12
  • Molecular formula

    C5H11NO2Se
  • PubChem identifier

    105024
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    O=C(O)[C@@H](N)CC[Se]C
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Ozten N  et al. L-Selenomethionine Does Not Protect Against Testosterone Plus 17ß-Estradiol-Induced Oxidative Stress and Preneoplastic Lesions in the Prostate of NBL Rats. Nutr Cancer :1-10 (2014). Read more (PubMed: 24773027) »
  • Nuth M & Kennedy AR Mitigating effects of L-selenomethionine on low-dose iron ion radiation-induced changes in gene expression associated with cellular stress. Oncol Lett 6:35-42 (2013). Read more (PubMed: 23946774) »
  • Guan J  et al. Effects of dietary supplements on the space radiation-induced reduction in total antioxidant status in CBA mice. Radiat Res 165:373-8 (2006). Read more (PubMed: 16579649) »

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
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