Overview

  • Product name

    L-5-Hydroxytryptophan, Serotonin precursor
  • Description

    Serotonin precursor
  • Biological description

    Serotonin precursor. Induces serotonin effects in vivo. Potentiates antidepressant effects. Orally active.
  • Purity

    > 98%
  • CAS Number

    4350-09-8
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (2S)-2-Amino-3-(5-hydroxy-1H-indol-3-yl)propanoic acid
  • Molecular weight

    220.22
  • Molecular formula

    C11H12N2O3
  • PubChem identifier

    439280
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Toxic, refer to SDS for further information.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C1=CC2=C(C=C1O)C(=CN2)CC(C(=O)O)N
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Sallinen J  et al. D-amphetamine and L-5-hydroxytryptophan-induced behaviours in mice with genetically-altered expression of the alpha2C-adrenergic receptor subtype. Neuroscience 86:959-65 (1998). Read more (PubMed: 9692731) »
  • Martin P  et al. Effects of triiodothyronine (T3) on the potentiation by antidepressants of L-5-hydroxytryptophan-induced head-twitches in mice. Prog Neuropsychopharmacol Biol Psychiatry 13:735-48 (1989). Read more (PubMed: 2789414) »
  • Rahman MK  et al. Effect of pyridoxal phosphate deficiency on aromatic L-amino acid decarboxylase activity with L-DOPA and L-5-hydroxytryptophan as substrates in rats. Jpn J Pharmacol 32:803-11 (1982). Read more (PubMed: 6983619) »

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