Key features and details
- Ca2+-insensitive PKC δ, ε and η activator
- CAS Number:
- Purity: > 98%
- Soluble in water to 5 mM
- Form / State: Solid
- Source: Synthetic
Product nameL-alpha-Phosphatidylinositol-3,4,5-trisphosphate sodium salt, PKC delta, epsilon and eta activator
DescriptionCa2+-insensitive PKC δ, ε and η activator
Activates Ca2+-insensitive PKC isotypes δ, ε and η in vitro. Binds to the general receptor for phosphoinositide-1 (GRP1) protein through a plekstrin homology (PH) domain.
Chemical name1,2-Dipalmitoyl-sn-glycero-3-phospho-1-D-myo-inositol-3,4,5-trisphosphate sodium salt
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in water to 5 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab145221 has been referenced in 1 publication.
- Owari T et al. Role of Nuclear Claudin-4 in Renal Cell Carcinoma. Int J Mol Sci 21:N/A (2020). PubMed: 33172177