L-Arginine hydrochloride, Nitrogen donor for synthesis of nitric oxide (ab145699)

Overview

  • Product name

    L-Arginine hydrochloride, Nitrogen donor for synthesis of nitric oxide
  • Description

    Nitrogen donor for the synthesis of nitric oxide
  • Alternative names

    • (S)-(+)-2-Amino-5-[(aminoiminomethyl)amino]pentanoic acid monohydrochloride
    • (S)-(+)-Arginine hydrochloride
    • Arginine hydrochloride
    • L-Arg
    • L-Arginine HCl
    see all
  • Biological description

    Substrate of nitric oxide synthase (NOS), which is converted to citrulline and nitric oxide (NO). Induces insulin release by a nitric oxide-dependent mechanism.

  • Purity

    > 99%
  • CAS Number

    1119-34-2
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (S)-2-Amino-5-guanidinopentanoic acid hydrochloride
  • Molecular weight

    210.66
  • Molecular formula

    C6H14N4O2.HCl
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • Source

    Synthetic

References

This product has been referenced in:

  • Morris CR  et al. Arginine therapy: a new treatment for pulmonary hypertension in sickle cell disease? Am J Respir Crit Care Med 168:63-9 (2003). Read more (PubMed: 12626350) »
  • Yamada M  et al. Endothelial nitric oxide synthase-dependent cerebral blood flow augmentation by L-arginine after chronic statin treatment. J Cereb Blood Flow Metab 20:709-17 (2000). Read more (PubMed: 10779015) »
  • Vergnani L  et al. Effect of native and oxidized low-density lipoprotein on endothelial nitric oxide and superoxide production : key role of L-arginine availability. Circulation 101:1261-6 (2000). Read more (PubMed: 10725285) »
  • Thams P & Capito K L-arginine stimulation of glucose-induced insulin secretion through membrane depolarization and independent of nitric oxide. Eur J Endocrinol 140:87-93 (1999). Read more (PubMed: 10037257) »
  • Huk I  et al. L-arginine treatment alters the kinetics of nitric oxide and superoxide release and reduces ischemia/reperfusion injury in skeletal muscle. Circulation 96:667-75 (1997). Read more (PubMed: 9244241) »

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab145699.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
For licensing inquiries, please contact partnerships@abcam.com

Sign up