Anti-L-Aspartate antibody (ab9439)

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Overview

  • Product name
    Anti-L-Aspartate antibody
  • Description
    Rabbit polyclonal to L-Aspartate
  • Host species
    Rabbit
  • Specificity
    The antibody is calibrated against a spectrum of antigens to assure hapten selectivity. No measurable cross-reactivity (<1:1000)was detected against aspartate in peptides or proteins. Fixed tissue cross-reactivity was tested with known targets at the recommended dilution. No measurable glutaraldehyde-fixed tissue cross-reactivity (<1:1000) was detected against L-alanine, gamma-aminobutyrate, agmatine, guanidine, D/L-arginine, L-citrulline, L-cysteine, D/L-glutamate, D/L-glutamine, glutathione, glycine, L-lysine, L-ornithine, L-serine, taurine, L-threonine, L-tryptophan, L-tyrosine. Significant cross-reactivity (1:10) was detected against D-aspartate.
  • Tested applications
    Suitable for: IHC-FoFr, IHC-Fr, ICC, Immunomicroscopymore details
  • Species reactivity
    Reacts with: Species independent
  • Immunogen

    Chemical/ Small Molecule by a Glutaraldehyde linker.

Properties

Applications

Our Abpromise guarantee covers the use of ab9439 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-FoFr Use at an assay dependent concentration.
IHC-Fr Use at an assay dependent concentration.
ICC Use at an assay dependent concentration.
Immunomicroscopy Use at an assay dependent concentration.

Target

  • Relevance
    Aspartic acid (Asp), also known as aspartate, is one of the 20 natural proteinogenic amino acids which are the building blocks of proteins. It is non-essential in mammals, and might serve as an excitatory neurotransmitter in the brain. It is also a metabolite in the urea cycle and participates in gluconeogenesis. As a neurotransmitter, aspartic acid may provide resistance to fatigue and thus lead to endurance, although the evidence to support this idea is not strong.
  • Alternative names
    • Aspartate antibody
    • Aspartic acid antibody
    • L ASP antibody
    • L aspartate antibody

References

This product has been referenced in:
See 1 Publication for this product

Publishing research using ab9439? Please let us know so that we can cite the reference in this datasheet.

Customer reviews and Q&As

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Question

Hello, I have a question about Anti-L-Aspartate antibody (ab9439). Would this Anti-L-Aspartate antibody work on mouse and/or human tissue?

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Answer


The immunogen of ab9439 is a Chemical / Small Molecule by a Glutaraldehyde linker. This is not species specific and therefore should work on mouse and/or human tissues however, we have not tested this.

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Question

Customer question: Looking to do IHC on paraffin embedded, glutaraldehyde fixed rat tissue for aspartate. Also ab6450 same question: Are these antibodies appropriate for this application

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Answer

I apologize for the delay with answering this question, I have only just heard back for the antibody's originator. Ab9439 - Has been tested on both paraffin embedded and frozen sections; No measurable glutaraldehyde-fixed tissue cross-reactivity (<1:1000) was detected against L-alanine, gamma-aminobutyrate, agmatine, guanidine, D/L-arginine, L-citrulline, L-cysteine, D/L-glutamate, D/L-glutamine, glutathione, glycine, L-lysine, L-ornithine, L-serine, taurine, L-threonine, L-tryptophan, L-tyrosine. For more information, please see online datasheet. Ab6450 - Has been tested on on paraffin embedded sections.

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