Overview

  • Product name

    L-Canavanine sulfate, iNOS inhibitor
  • Description

    Selective iNOS inhibitor
  • Biological description

    Selective iNOS inhibitor. L-Arginine (ab120750) analog. Inhibits cGMP response to endothelin-1 (IC50 = 60 μM). Shows antihypotensive effects in vivo.
  • CAS Number

    2219-31-0
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Melangeli C  et al. The biochemical basis for L-canavanine tolerance by the tobacco budworm Heliothis virescens (Noctuidae). Proc Natl Acad Sci U S A 94:2255-60 (1997). Read more (PubMed: 9122181) »
  • Liaudet L  et al. Beneficial effects of L-canavanine, a selective inhibitor of inducible nitric oxide synthase, during rodent endotoxaemia. Clin Sci (Lond) 90:369-77 (1996). Read more (PubMed: 8665774) »
  • Teale DM & Atkinson AM L-canavanine restores blood pressure in a rat model of endotoxic shock. Eur J Pharmacol 271:87-92 (1994). Read more (PubMed: 7535234) »

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