Key features and details
- Dopamine (ab120565) precursor
- CAS Number: 59-92-7
- Purity: > 99%
- Soluble in water to 5 mM and in 1 eq. HCl to 100 mM
- Form / State: Solid
- Source: Synthetic
Product nameL-DOPA, Dopamine (ab120565) precursor
DescriptionDopamine (ab120565) precursor
Dopamine (ab120565) precursor. Blood-brain barrier permeable. Increases dopamine levels in Parkinson's disease models to display anti-Parkinson's disease properties.
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in water to 5 mM and in 1 eq. HCl to 100 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab120573 has been referenced in 6 publications.
- Robles-Murguia M et al. Muscle-derived Dpp regulates feeding initiation via endocrine modulation of brain dopamine biosynthesis. Genes Dev 34:37-52 (2020). PubMed: 31831628
- Sun F et al. A Genetically Encoded Fluorescent Sensor Enables Rapid and Specific Detection of Dopamine in Flies, Fish, and Mice. Cell 174:481-496.e19 (2018). PubMed: 30007419
- Ono K et al. Cutaneous pigmentation modulates skin sensitivity via tyrosinase-dependent dopaminergic signalling. Sci Rep 7:9181 (2017). PubMed: 28835637
- Massari CM et al. Antiparkinsonian Efficacy of Guanosine in Rodent Models of Movement Disorder. Front Pharmacol 8:700 (2017). PubMed: 29046640
- Fernández-Dueñas V et al. Untangling dopamine-adenosine receptor-receptor assembly in experimental parkinsonism in rats. Dis Model Mech 8:57-63 (2015). PubMed: 25398851
- Wu K et al. Plant phenolics are detoxified by prophenoloxidase in the insect gut. Sci Rep 5:16823 (2015). PubMed: 26592948