Overview

  • Product name

    L-Glutamine, Amino acid
  • Description

    Amino acid
  • Alternative names

    • Gln
    • Q
  • Biological description

    Amino acid. Major respiratory fuel and substrate for nucleic acid synthesis in mammalian intestinal cells. Inhibits the generation of L-Arginine by cultured endothelial cells.

  • Purity

    > 99%
  • CAS Number

    56-85-9
  • Chemical structure

    Chemical Structure

Properties

  • Molecular weight

    146.14
  • Molecular formula

    C5H10N2O3
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • Source

    Synthetic

References

This product has been referenced in:

  • Svoboda N & Kerschbaum HH L-Glutamine-induced apoptosis in microglia is mediated by mitochondrial dysfunction. Eur J Neurosci 30:196-206 (2009). Read more (PubMed: 19614980) »
  • Haynes TE  et al. L-Glutamine or L-alanyl-L-glutamine prevents oxidant- or endotoxin-induced death of neonatal enterocytes. Amino Acids 37:131-42 (2009). Read more (PubMed: 19189199) »
  • Rhoads JM  et al. L-glutamine and L-asparagine stimulate Na+ -H+ exchange in porcine jejunal enterocytes. Am J Physiol 266:G828-38 (1994). Read more (PubMed: 8203529) »
  • Hecker M  et al. Inhibition by L-glutamine of the release of endothelium-derived relaxing factor from cultured endothelial cells. Br J Pharmacol 101:237-9 (1990). Read more (PubMed: 2257431) »
  • Sessa WC  et al. The metabolism of L-arginine and its significance for the biosynthesis of endothelium-derived relaxing factor: L-glutamine inhibits the generation of L-arginine by cultured endothelial cells. Proc Natl Acad Sci U S A 87:8607-11 (1990). Read more (PubMed: 1978327) »

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