Overview

  • Product name

    L-threo-PDMP
  • Description

    Enantiomer of D-threo-PDMP
  • Biological description

    Enantiomer of D-threo-PDMP (Asc 4052). Activates glycosyltransferases for ganglioside biosynthesis. Antineurodegenerative properties. Active in vivo and in vitro.

    See similar compounds
  • Purity

    > 98%
  • CAS Number

    109836-81-9
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    N-[(1S,2S)-1-Hydroxy-3-morpholin-4-yl-1-phenylpropan-2-yl]decanamide hydrochloride
  • Molecular weight

    427.03
  • Molecular formula

    C23H38N2O3.HCl
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in ethanol
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    Cl.CCCCCCCCCC(=O)N[C@@H](CN1CCOCC1)[C@@H](O)c2ccccc2
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Inokuchi J Neurotrophic and neuroprotective actions of an enhancer of ganglioside biosynthesis. Int Rev Neurobiol 85:319-36 (2009). Read more (PubMed: 19607978) »
  • Inokuchi J  et al. Stimulation of glycosphingolipid biosynthesis by L-threo-1-phenyl-2-decanoylamino-1-propanol and its homologs in B16 melanoma cells. J Biochem 117:766-73 (1995). Read more (PubMed: 7592537) »

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